Masaaki Komatsu
Overview
Explore the profile of Masaaki Komatsu including associated specialties, affiliations and a list of published articles.
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271
Citations
38169
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Recent Articles
11.
Asada K, Kaneko S, Takasawa K, Shiraishi K, Shinkai N, Shimada Y, et al.
Mol Cancer
. 2024 Sep;
23(1):182.
PMID: 39218851
Background: The cancer genome contains several driver mutations. However, in some cases, no known drivers have been identified; these remaining areas of unmet needs, leading to limited progress in cancer...
12.
Kato M, Fujii E, Yamaguchi M, Higuchi D, Asami Y, Hiranuma K, et al.
Gynecol Oncol
. 2024 Aug;
190:139-145.
PMID: 39191063
Objective: The 2023 International Federation of Gynecology and Obstetrics classification with molecular classification shows superior discriminatory ability compared to staging systems lacking molecular data. However, the accuracy of endometrial biopsy...
13.
Takada S, Komatsu M, Morishita H
Methods Mol Biol
. 2024 Aug;
2845:191-196.
PMID: 39115667
p62 bodies are ubiquitin-positive cytoplasmic condensates formed by liquid-liquid phase separation. They are targeted by selective autophagy and play important roles in intracellular quality control and stress responses. However, little...
14.
Kaneko S, Takasawa K, Asada K, Shiraishi K, Ikawa N, Machino H, et al.
Mol Cancer
. 2024 Jun;
23(1):126.
PMID: 38862995
Background: In an extensive genomic analysis of lung adenocarcinomas (LUADs), driver mutations have been recognized as potential targets for molecular therapy. However, there remain cases where target genes are not...
15.
Fujii E, Kato M, Yamaguchi M, Higuchi D, Koyama T, Komatsu M, et al.
Sci Rep
. 2024 Jun;
14(1):13058.
PMID: 38844774
The incidence of vulvar carcinoma varies by race; however, it is a rare disease, and its genomic profiles remain largely unknown. This study examined the characteristics of vulvar squamous cell...
16.
Chen X, Tsvetkov A, Shen H, Isidoro C, Ktistakis N, Linkermann A, et al.
Autophagy
. 2024 Mar;
20(6):1213-1246.
PMID: 38442890
Macroautophagy/autophagy is a complex degradation process with a dual role in cell death that is influenced by the cell types that are involved and the stressors they are exposed to....
17.
Kato M, Fujii E, Asami Y, Momozawa Y, Hiranuma K, Komatsu M, et al.
Cancer Sci
. 2024 Mar;
115(5):1646-1655.
PMID: 38433331
The clinical features of sporadic mismatch repair deficiency (MMRd) and Lynch syndrome (LS) in Japanese patients with endometrial cancer (EC) were examined by evaluating the prevalence and prognostic factors of...
18.
Takasawa K, Asada K, Kaneko S, Shiraishi K, Machino H, Takahashi S, et al.
Exp Mol Med
. 2024 Mar;
56(3):646-655.
PMID: 38433247
DNA methylation is an epigenetic modification that results in dynamic changes during ontogenesis and cell differentiation. DNA methylation patterns regulate gene expression and have been widely researched. While tools for...
19.
Komatsu M, Inada T, Noda N
Mol Cell
. 2023 Dec;
84(1):156-169.
PMID: 38141606
Ubiquitin-fold modifier 1 (UFM1) is a ubiquitin-like protein covalently conjugated with intracellular proteins through UFMylation, a process similar to ubiquitylation. Growing lines of evidence regarding not only the structural basis...
20.
Kurusu R, Morishita H, Komatsu M
J Biochem
. 2023 Nov;
175(2):141-146.
PMID: 37948628
Cellular zoning or partitioning is critical in preventing macromolecules from random diffusion and orchestrating the spatiotemporal dynamics of biochemical reactions. Along with membranous organelles, membraneless organelles contribute to the precise...