Marzia Perluigi
Overview
Explore the profile of Marzia Perluigi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
135
Citations
4386
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0
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Recent Articles
11.
Urbinati C, Lanzillotta C, Cosentino L, Valenti D, Quattrini M, Di Crescenzo L, et al.
Neuropharmacology
. 2022 Nov;
224:109350.
PMID: 36442649
Metformin is the most common anti-diabetic drug and a promising therapy for disorders beyond diabetes, including Rett syndrome (RTT), a rare neurologic disease characterized by severe intellectual disability. A 10-day-long...
12.
Cimini F, Perluigi M, Barchetta I, Cavallo M, Barone E
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628384
Insulin signaling is a conserved pathway that orchestrates glucose and lipid metabolism, energy balance, and inflammation, and its dysregulation compromises the homeostasis of multiple systems. Insulin resistance is a shared...
13.
Perluigi M, Barone E
Nat Rev Neurol
. 2022 Mar;
18(5):255-256.
PMID: 35301457
No abstract available.
14.
Pagnotta S, Tramutola A, Barone E, Di Domenico F, Pittala V, Salerno L, et al.
Free Radic Biol Med
. 2022 Mar;
183:1-13.
PMID: 35283228
The cells possess several mechanisms to counteract the over-production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), including enzymes such as superoxide dismutase, catalase and glutathione peroxidase. Moreover,...
15.
Perluigi M, Picca A, Montanari E, Calvani R, Marini F, Matassa R, et al.
Alzheimers Dement
. 2021 Nov;
18(8):1498-1510.
PMID: 34812584
Introduction: Intellectual disability, accelerated aging, and early-onset Alzheimer-like neurodegeneration are key brain pathological features of Down syndrome (DS). Although growing research aims at the identification of molecular pathways underlying the...
16.
Barone E, Di Domenico F, Perluigi M, Butterfield D
Free Radic Biol Med
. 2021 Sep;
176:16-33.
PMID: 34530075
Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has been reported in diabetic...
17.
Dierssen M, Herault Y, Helguera P, Martinez de Lagran M, Vazquez A, Christian B, et al.
Mol Syndromol
. 2021 Aug;
12(4):202-218.
PMID: 34421499
Research focused on Down syndrome has increased in the last several years to advance understanding of the consequences of trisomy 21 (T21) on molecular and cellular processes and, ultimately, on...
18.
Zuliani I, Lanzillotta C, Tramutola A, Barone E, Perluigi M, Rinaldo S, et al.
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33916835
The disturbance of protein O-GlcNAcylation is emerging as a possible link between altered brain metabolism and the progression of neurodegeneration. As observed in brains with Alzheimer's disease (AD), flaws of...
19.
Lanzillotta C, Tramutola A, Di Giacomo G, Marini F, Butterfield D, Di Domenico F, et al.
Free Radic Biol Med
. 2021 Jan;
165:152-170.
PMID: 33516914
Dysregulation of brain insulin signaling with reduced downstream neuronal survival and plasticity mechanisms are fundamental abnormalities observed in Alzheimer disease (AD). This phenomenon, known as brain insulin resistance, is associated...
20.
Tramutola A, Perluigi M
Methods Mol Biol
. 2021 Jan;
2261:79-91.
PMID: 33420986
Posttranslational modifications (PTMs) of a protein are chemical modifications that play a key role because they regulate almost all cellular events, including gene expression, signal transduction, protein-protein interaction, cell-cell interaction,...