Chiara Lanzillotta
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Explore the profile of Chiara Lanzillotta including associated specialties, affiliations and a list of published articles.
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32
Citations
488
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Recent Articles
1.
Lanzillotta S, Esteve D, Lanzillotta C, Tramutola A, Lloret A, Forte E, et al.
Free Radic Biol Med
. 2024 Nov;
227():80-93.
PMID: 39586382
Down Syndrome (DS) is a genetic disorder caused by the presence of an extra copy of chromosome 21, and leading to various developmental and cognitive defects. A critical feature of...
2.
Cosentino L, Urbinati C, Lanzillotta C, De Rasmo D, Valenti D, Pellas M, et al.
Mol Autism
. 2024 Sep;
15(1):39.
PMID: 39300547
Background: Defective mitochondria and aberrant brain mitochondrial bioenergetics are consistent features in syndromic intellectual disability disorders, such as Rett syndrome (RTT), a rare neurologic disorder that severely affects mainly females...
3.
Lanzillotta C, Tramutola A, Lanzillotta S, Greco V, Pagnotta S, Sanchini C, et al.
Redox Biol
. 2024 Jun;
73:103221.
PMID: 38843768
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain...
4.
Lanzillotta C, Baniowska M, Prestia F, Sette C, Nalesso V, Perluigi M, et al.
Neurobiol Dis
. 2024 May;
196:106523.
PMID: 38705491
Down syndrome (DS) is the most common condition with intellectual disability and is caused by trisomy of Homo sapiens chromosome 21 (HSA21). The increased dosage of genes on HSA21 is...
5.
Di Domenico F, Lanzillotta C, Perluigi M
FEBS Lett
. 2024 Mar;
598(17):2047-2066.
PMID: 38472147
Redox reactions play a critical role for intracellular processes, including pathways involved in metabolism and signaling. Reactive oxygen species (ROS) act either as second messengers or generators of protein modifications,...
6.
Cimini F, Tramutola A, Barchetta I, Ceccarelli V, Gangitano E, Lanzillotta S, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108445
Biliverdin reductase-A (BVRA) is involved in the regulation of insulin signaling and the maintenance of glucose homeostasis. Previous research showed that BVRA alterations are associated with the aberrant activation of...
7.
Urbinati C, Lanzillotta C, Cosentino L, Valenti D, Quattrini M, Di Crescenzo L, et al.
Neuropharmacology
. 2022 Nov;
224:109350.
PMID: 36442649
Metformin is the most common anti-diabetic drug and a promising therapy for disorders beyond diabetes, including Rett syndrome (RTT), a rare neurologic disease characterized by severe intellectual disability. A 10-day-long...
8.
Di Domenico F, Lanzillotta C
Adv Protein Chem Struct Biol
. 2022 Sep;
132:49-87.
PMID: 36088079
Protein homeostasis or "proteostasis" represent the process that regulates the balance of the intracellular functional and "healthy" proteins. Proteostasis is fundamental to preserve physiological metabolic processes in the cell and...
9.
Zuliani I, Lanzillotta C, Tramutola A, Barone E, Perluigi M, Rinaldo S, et al.
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33916835
The disturbance of protein O-GlcNAcylation is emerging as a possible link between altered brain metabolism and the progression of neurodegeneration. As observed in brains with Alzheimer's disease (AD), flaws of...
10.
Lanzillotta C, Di Domenico F
Biomolecules
. 2021 Mar;
11(2).
PMID: 33670211
Down syndrome (DS) is the most common genomic disorder characterized by the increased incidence of developing early Alzheimer's disease (AD). In DS, the triplication of genes on chromosome 21 is...