Marzia Perluigi
Overview
Explore the profile of Marzia Perluigi including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
4386
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0
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Recent Articles
1.
Lanzillotta S, Esteve D, Lanzillotta C, Tramutola A, Lloret A, Forte E, et al.
Free Radic Biol Med
. 2024 Nov;
227():80-93.
PMID: 39586382
Down Syndrome (DS) is a genetic disorder caused by the presence of an extra copy of chromosome 21, and leading to various developmental and cognitive defects. A critical feature of...
2.
Giallongo S, Ferrigno J, Caltabiano R, Broggi G, Alanazi A, Distefano A, et al.
Aging (Albany NY)
. 2024 Jun;
16(12):10203-10215.
PMID: 38942607
Down Syndrome (DS) is a common genetic disorder characterized by an extra copy of chromosome 21, leading to dysregulation of various metabolic pathways. Oxidative stress in DS is associated with...
3.
Lanzillotta C, Tramutola A, Lanzillotta S, Greco V, Pagnotta S, Sanchini C, et al.
Redox Biol
. 2024 Jun;
73:103221.
PMID: 38843768
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain...
4.
Lanzillotta C, Baniowska M, Prestia F, Sette C, Nalesso V, Perluigi M, et al.
Neurobiol Dis
. 2024 May;
196:106523.
PMID: 38705491
Down syndrome (DS) is the most common condition with intellectual disability and is caused by trisomy of Homo sapiens chromosome 21 (HSA21). The increased dosage of genes on HSA21 is...
5.
Staurenghi E, Testa G, Leoni V, Cecci R, Floro L, Giannelli S, et al.
Antioxidants (Basel)
. 2024 Apr;
13(4).
PMID: 38671883
Down syndrome (DS) is a complex chromosomal disorder considered as a genetically determined form of Alzheimer's disease (AD). Maintenance of brain cholesterol homeostasis is essential for brain functioning and development,...
6.
Di Domenico F, Lanzillotta C, Perluigi M
FEBS Lett
. 2024 Mar;
598(17):2047-2066.
PMID: 38472147
Redox reactions play a critical role for intracellular processes, including pathways involved in metabolism and signaling. Reactive oxygen species (ROS) act either as second messengers or generators of protein modifications,...
7.
Tramutola A, Bakels H, Perrone F, Di Nottia M, Mazza T, Abruzzese M, et al.
EBioMedicine
. 2023 Oct;
97:104849.
PMID: 37898095
Background: Paediatric Huntington disease with highly expanded mutations (HE-PHD; >80 CAG repeats) presents atypically, compared to adult-onset Huntington disease (AOHD), with neurodevelopmental delay, epilepsy, abnormal brain glucose metabolism, early striatal...
8.
Rotondo R, Proietti S, Perluigi M, Padua E, Stocchi F, Fini M, et al.
Ageing Res Rev
. 2023 Oct;
92:102089.
PMID: 37844764
Parkinson's disease (PD) is a neurodegenerative disorder, characterized by motor and non-motor symptoms, that still lacks of a disease-modifying treatment. Consistent evidence proved the benefits of physical therapy on motor...
9.
Perluigi M, Di Domenico F, Butterfield D
Physiol Rev
. 2023 Oct;
104(1):103-197.
PMID: 37843394
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms, among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises in various pathways regulating brain functions,...
10.
Tramutola A, Lanzillotta S, Aceto G, Pagnotta S, Ruffolo G, Cifelli P, et al.
Antioxidants (Basel)
. 2023 Jan;
12(1).
PMID: 36670973
Down syndrome (DS) is the most frequent genetic cause of intellectual disability and is strongly associated with Alzheimer's disease (AD). Brain insulin resistance greatly contributes to AD development in the...