Marwa E Abdelaziz
Overview
Explore the profile of Marwa E Abdelaziz including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
24
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Recent Articles
1.
Mohamed A, Alshammari M, Aly A, Sadek K, Ahmad A, Aziz E, et al.
J Enzyme Inhib Med Chem
. 2024 Mar;
39(1):2311818.
PMID: 38488131
In this article, a new series of 2-((3,5-disubstituted-2-thioxo-imidazol-1-yl)imino)acenaphthylen-1(2)-ones were synthesized. Imidazole-2-thione with acenaphthylen-one gave a hybrid scaffold that integrated key structural elements essential for DNA damage direct DNA intercalation and...
2.
Abdelaziz M, El-Miligy M, Fahmy S, Abu-Serie M, Hazzaa A, Mahran M
J Enzyme Inhib Med Chem
. 2024 Jan;
39(1):2304044.
PMID: 38230430
New aromatic -alkyl pyridine derivatives were designed and synthesised as Proviral Integration Moloney (PIM)-1 kinase inhibitors. and showed potent anticancer activity against NFS-60, HepG-2, PC-3, and Caco-2 cell lines and...
3.
El-Miligy M, Abdelaziz M, Fahmy S, Ibrahim T, Abu-Serie M, Mahran M, et al.
J Enzyme Inhib Med Chem
. 2023 Jan;
38(1):2152810.
PMID: 36629075
New quinoline-pyridine hybrids were designed and synthesised as PIM-1/2 kinase inhibitors. Compounds , , , and showed low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent anticancer...
4.
Abdelaziz M, El-Miligy M, Fahmy S, Mahran M, Hazzaa A
Bioorg Chem
. 2018 Aug;
80:674-692.
PMID: 30064079
A series of pyridine and thieno[2,3-b]pyridine derivatives have been designed and synthesized as anticancer PIM-1 kinase inhibitors. Thirty-seven compounds were selected by NCI to be tested initially at a single...