Martin Klapper
Overview
Explore the profile of Martin Klapper including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
113
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bando Y, Klapper M, Herbst R, Sachse A, Stallforth P, Arndt H
Org Lett
. 2025 Mar;
PMID: 40062948
The total synthesis of -derived cyclic lipodepsipeptide anikasin was achieved. Using a depsipeptide building block and balanced protecting groups on the branching d--Thr residue, the synthesis was established semiautomatically on...
2.
Klapper M, Stallforth P
Microlife
. 2024 Dec;
5:uqae023.
PMID: 39660047
Microbial natural products-low molecular weight compounds biosynthesized by microorganisms-form the foundation of important modern therapeutics, including antibiotics, immunomodulators, and anti-cancer agents. This perspective discusses and contrasts two emerging approaches for...
3.
Zdouc M, Blin K, Louwen N, Navarro J, Loureiro C, Bader C, et al.
Nucleic Acids Res
. 2024 Dec;
53(D1):D678-D690.
PMID: 39657789
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is...
4.
Klapper M, Hubner A, Ibrahim A, Wasmuth I, Borry M, Haensch V, et al.
Science
. 2023 May;
380(6645):619-624.
PMID: 37141315
Major advances over the past decade in the field of ancient DNA are providing access to past paleogenomic diversity, but the diverse functions and biosynthetic capabilities of this growing paleome...
5.
Gotze S, Arp J, Lackner G, Zhang S, Kries H, Klapper M, et al.
Chem Sci
. 2020 Sep;
10(48):10979-10990.
PMID: 32953002
Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites indispensable in the treatment of cancer or...
6.
Klapper M, Schlabach K, Paschold A, Zhang S, Chowdhury S, Menzel K, et al.
Angew Chem Int Ed Engl
. 2019 Dec;
59(14):5607-5610.
PMID: 31880848
Butenolides are well-known signaling molecules in Gram-positive bacteria. Here, we describe a novel class of butenolides isolated from a Gram-negative Pseudomonas strain, the styrolides. Structure elucidation was aided by the...
7.
Klapper M, Paschold A, Zhang S, Weigel C, Dahse H, Gotze S, et al.
ACS Chem Biol
. 2019 Jul;
14(8):1693-1697.
PMID: 31294961
Microbially produced 3-acyltetramic acids display a diverse range of biological activities. The pyreudiones are new members of this class that were isolated from bacteria of the genus . Here, we...
8.
Klapper M, Braga D, Lackner G, Herbst R, Stallforth P
Cell Chem Biol
. 2018 Apr;
25(6):659-665.e9.
PMID: 29606578
Chemical and biochemical analyses of one of the most basic nonribosomal peptide synthetases (NRPS) from a Pseudomonas fluorescens strain revealed its striking plasticity. Determination of the potential substrate scope enabled...
9.
Arp J, Gotze S, Mukherji R, Mattern D, Garcia-Altares M, Klapper M, et al.
Proc Natl Acad Sci U S A
. 2018 Mar;
115(15):3758-3763.
PMID: 29592954
Investigating microbial interactions from an ecological perspective is a particularly fruitful approach to unveil both new chemistry and bioactivity. Microbial predator-prey interactions in particular rely on natural products as signal...
10.
Gotze S, Herbst-Irmer R, Klapper M, Gorls H, Schneider K, Barnett R, et al.
ACS Chem Biol
. 2017 Aug;
12(10):2498-2502.
PMID: 28846366
The class of cyclic lipopeptide natural products consists of compounds with a diverse range of bioactivities. In this study, we elucidated the structure of the cyclic lipopeptide anikasin using X-ray...