Martin J McGavin
Overview
Explore the profile of Martin J McGavin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
940
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kuiack R, Tuffs S, Dufresne K, Flick R, McCormick J, McGavin M
Mol Microbiol
. 2023 Jul;
120(3):425-438.
PMID: 37501506
In Staphylococcus aureus, genes that should confer the capacity to metabolize fatty acids by β-oxidation occur in the fadXDEBA locus, but their function has not been elucidated. Previously, incorporation into...
2.
Bonn C, Rafiqullah I, Crawford J, Qian Y, Guthrie J, Matuszewska M, et al.
Antimicrob Agents Chemother
. 2023 Feb;
67(3):e0074922.
PMID: 36744906
Resistance-nodulation-division (RND) superfamily efflux pumps promote antibiotic resistance in Gram-negative pathogens, but their role in Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) is undocumented. However, recent selections for resistance of...
3.
Kuiack R, Veldhuizen R, McGavin M
J Bacteriol
. 2020 Sep;
202(22).
PMID: 32868405
Although the GraS sensor kinase of is known for the sensing of and resistance to cationic antimicrobial peptides (CAMPs), we recently established that it also signals in response to acidic...
4.
El-Halfawy O, Czarny T, Flannagan R, Day J, Bozelli Jr J, Kuiack R, et al.
Nat Chem Biol
. 2019 Nov;
16(2):143-149.
PMID: 31768032
Staphylococcus aureus is the leading cause of infections worldwide, and methicillin-resistant strains (MRSA) are emerging. New strategies are urgently needed to overcome this threat. Using a cell-based screen of ~45,000...
5.
Goncheva M, Flannagan R, Sterling B, Laakso H, Friedrich N, Kaiser J, et al.
Nat Commun
. 2019 Feb;
10(1):775.
PMID: 30770821
Staphylococcus aureus is a significant cause of human infection. Here, we demonstrate that mutations in the transcriptional repressor of purine biosynthesis, purR, enhance the pathogenic potential of S. aureus. Indeed,...
6.
Alnaseri H, Kuiack R, Ferguson K, Schneider J, Heinrichs D, McGavin M
J Bacteriol
. 2018 Nov;
201(3).
PMID: 30455282
Divergent genes in USA300 encode the efflux pump FarE and TetR family regulator FarR, which confer resistance to antimicrobial unsaturated fatty acids. To study their regulation, we constructed USA300 Δ,...
7.
Flannagan R, Kuiack R, McGavin M, Heinrichs D
mBio
. 2018 Jul;
9(4).
PMID: 30018109
Macrophages are critical to innate immunity due to their ability to phagocytose bacteria. The macrophage phagolysosome is a highly acidic organelle with potent antimicrobial properties, yet remarkably, ingested replicates within...
8.
Alnaseri H, Arsic B, Schneider J, Kaiser J, Scinocca Z, Heinrichs D, et al.
J Bacteriol
. 2015 Mar;
197(11):1893-905.
PMID: 25802299
Unlabelled: Although Staphylococcus aureus is exposed to antimicrobial fatty acids on the skin, in nasal secretions, and in abscesses, a specific mechanism of inducible resistance to this important facet of...
9.
Sayedyahossein S, Xu S, Rudkouskaya A, McGavin M, McCormick J, Dagnino L
FASEB J
. 2014 Nov;
29(2):711-23.
PMID: 25416549
Staphylococcus aureus is a major component of the skin microbiota and causes a large number of serious infections. S. aureus first interacts with epidermal keratinocytes to breach the epidermal barrier...
10.
Cadieux B, Vijayakumaran V, Bernards M, McGavin M, Heinrichs D
J Bacteriol
. 2014 Sep;
196(23):4044-56.
PMID: 25225262
Part of the human host innate immune response involves the secretion of bactericidal lipids on the skin and delivery of triglycerides into abscesses to control invading pathogens. Two Staphylococcus aureus...