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Martijn C Nawijn

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Articles 106
Citations 2945
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Recent Articles
1.
Berg M, Krabbendam L, van der Ploeg E, van Nimwegen M, van der Veer T, Banchero M, et al.
J Cyst Fibros . 2025 Feb; PMID: 39947933
Background: Chronic pulmonary inflammation strongly contributes to respiratory failure and mortality in patients with cystic fibrosis (pwCF). Effective anti-microbial immunity and maintaining lung homeostasis require continuous structural-immune cell communication. Whether...
2.
van Baarle D, Nawijn M
Nat Immunol . 2025 Jan; 26(2):152-154. PMID: 39880999
No abstract available.
3.
El-Husseini Z, Karp T, Lan A, Gillett T, Qi C, Khalenkow D, et al.
Am J Respir Cell Mol Biol . 2025 Jan; PMID: 39836087
Asthma is a genetically complex inflammatory airway disease associated with over 200 Single nucleotide polymorphisms (SNPs). However, the functional effects of many asthma-associated SNPs in lung and airway epithelial samples...
4.
Portelli M, Ketelaar M, Bates S, Csomor E, Shaw D, Emsley J, et al.
Clin Exp Allergy . 2024 Sep; 54(12):984-995. PMID: 39301832
Introduction: The interleukin-33/interleukin-1 receptor-like-1 (IL-33/IL1RL1) signalling pathway is implicated in asthma pathogenesis, with IL1RL1 nonsynonymous genetic polymorphisms associated with disease risk. We aimed to determine these variants' effect on IL1RL1...
5.
Vlasma J, van der Veen T, de Jager M, Nawijn M, Brandsma C, Melgert B
Am J Physiol Lung Cell Mol Physiol . 2024 Sep; 327(5):L634-L645. PMID: 39254089
Epidemiological studies have shown that smoking is associated with increased incidence of severe viral infections leading to hospitalization. Moreover, studies in experimental models have identified impaired antiviral responses and altered...
6.
Karp T, Faiz A, van Nijnatten J, Kerstjens H, Boudewijn I, Kraft M, et al.
Thorax . 2024 Jul; 79(10):905-914. PMID: 39009441
Introduction: Asthma is an inflammatory airways disease encompassing multiple phenotypes and endotypes. Several studies suggested gene expression in nasal epithelium to serve as a proxy for bronchial epithelium, being a...
7.
Kole T, Muiser S, Kraft M, Siddiqui S, Fabbri L, Rabe K, et al.
BMJ Open Respir Res . 2024 Jun; 11(1). PMID: 38901877
Background: Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients. Question: What are differences between male and female patients with asthma with...
8.
Saikumar Jayalatha A, Ketelaar M, Hesse L, Badi Y, Zounemat-Kermani N, Brouwer S, et al.
Eur Respir J . 2024 Jun; 63(6). PMID: 38843913
No abstract available.
9.
Jimenez-Gracia L, Marchese D, Nieto J, Caratu G, Melon-Ardanaz E, Gudino V, et al.
Genome Biol . 2024 Mar; 25(1):81. PMID: 38553769
The use of single-cell technologies for clinical applications requires disconnecting sampling from downstream processing steps. Early sample preservation can further increase robustness and reproducibility by avoiding artifacts introduced during specimen...
10.
Visser N, Herreman L, Vandooren J, Pereira R, Opdenakker G, Spelbrink R, et al.
J Mol Med (Berl) . 2024 Feb; 102(4):521-536. PMID: 38381158
Viruses critically rely on various proteases to ensure host cell entry and replication. In response to viral infection, the host will induce acute tissue inflammation pulled by granulocytes. Upon hyperactivation,...