Wim Timens
Overview
Explore the profile of Wim Timens including associated specialties, affiliations and a list of published articles.
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305
Citations
9926
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Recent Articles
1.
Dalapati T, Wang L, Jones A, Cardwell J, Konigsberg I, Bosse Y, et al.
HGG Adv
. 2025 Jan;
6(2):100410.
PMID: 39876559
Most genetic variants identified through genome-wide association studies (GWASs) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated...
2.
El-Husseini Z, Karp T, Lan A, Gillett T, Qi C, Khalenkow D, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39836087
Asthma is a genetically complex inflammatory airway disease associated with over 200 Single nucleotide polymorphisms (SNPs). However, the functional effects of many asthma-associated SNPs in lung and airway epithelial samples...
3.
Thunnissen E, Blaauwgeers H, Filipello F, Lissenberg-Witte B, Minami Y, Noguchi M, et al.
Lung Cancer
. 2025 Jan;
199:108060.
PMID: 39793325
Objectives: Evaluating invasion in non-mucinous adenocarcinoma (NMA) of the lung is crucial for accurate pT-staging. This study compares the World Health Organization (WHO) with a recently modified NMA classification. Materials...
4.
Gorman B, Ji S, Francis M, Sendamarai A, Shi Y, Devineni P, et al.
Nat Commun
. 2024 Oct;
15(1):8629.
PMID: 39366959
Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and...
5.
Ilie M, Lake V, de Alava E, Bonin S, Chlebowski S, Delort A, et al.
Virchows Arch
. 2024 Oct;
485(5):761-775.
PMID: 39354109
Despite advancements in precision medicine, many cancer patients globally, particularly those in resource-constrained environments, face significant challenges in accessing high-quality molecular testing and targeted therapies. The considerable heterogeneity in molecular...
6.
Al-Adwi Y, Westra J, Goor H, van Kempen L, Osman M, Gan C, et al.
J Autoimmun
. 2024 Aug;
148:103297.
PMID: 39098251
Objective: Systemic sclerosis-interstitial lung disease (SSc-ILD) is the leading cause of death in SSc, affecting around 50 % of the patients. Lung tissue of patients with early-stage SSc-ILD is characterized...
7.
Dalapati T, Wang L, Jones A, Cardwell J, Konigsberg I, Bosse Y, et al.
medRxiv
. 2024 Jul;
PMID: 39040187
Most genetic variants identified through genome-wide association studies (GWAS) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated...
8.
Joglekar M, Bekker N, Koloko Ngassie M, Vonk J, Borghuis T, Reinders-Luinge M, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Jun;
327(3):L304-L318.
PMID: 38915286
Extracellular matrix (ECM) remodeling has been implicated in the irreversible obstruction of airways and destruction of alveolar tissue in chronic obstructive pulmonary disease (COPD). Studies investigating differences in the lung...
9.
Bartel S, Wolters J, Noor H, Rafie K, Fang J, Kirchner B, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891077
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease for which there is no cure. Accumulating research results suggest a role for extracellular vesicles (EVs) in the pathogenesis of...
10.
Blaauwgeers H, Dickhoff C, Pelosi G, Timens W, Filipello F, Minami Y, et al.
J Thorac Oncol
. 2024 May;
19(5):671-676.
PMID: 38719423
No abstract available.