Martha L Funderburgh
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Explore the profile of Martha L Funderburgh including associated specialties, affiliations and a list of published articles.
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31
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1346
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Recent Articles
1.
Santra M, Hsu Y, Khadem S, Radencic S, Funderburgh M, Sawant O, et al.
Bio Protoc
. 2024 Sep;
14(18):e5074.
PMID: 39346761
Corneal scarring, a significant cause of global blindness, results from various insults, including trauma, infections, and genetic disorders. The conventional treatment to replace scarred corneal tissues includes partial or full-thickness...
2.
Santra M, Geary M, Funderburgh M, Yam G
Methods Mol Biol
. 2024 Sep;
2848:3-23.
PMID: 39240513
The challenge of treating corneal scarring through keratoplasties lies in the limited availability of donor tissue. Various studies have shown the therapeutic use of cultivated corneal stromal stem cells (CSSCs)...
3.
Santra M, Geary M, Rubin E, Hsu M, Funderburgh M, Chandran C, et al.
Stem Cell Res Ther
. 2024 Jan;
15(1):11.
PMID: 38185673
Background: Mesenchymal stem cells in the adult corneal stroma (named corneal stromal stem cells, CSSCs) inhibit corneal inflammation and scarring and restore corneal clarity in pre-clinical corneal injury models. This...
4.
Dos Santos A, Lyu N, Balayan A, Knight R, Zhuo K, Sun Y, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362184
In addition to their therapeutic potential in regenerative medicine, human corneal stromal stem cells (CSSCs) could serve as a powerful tool for drug discovery and development. Variations from different donors,...
5.
Kumar A, Yun H, Funderburgh M, Du Y
Prog Retin Eye Res
. 2021 Sep;
87:101011.
PMID: 34530154
The cornea is the outmost layer of the eye, unique in its transparency and strength. The cornea not only transmits the light essential for vision, also refracts light, giving focus...
6.
Weng L, Funderburgh J, Khandaker I, Geary M, Yang T, Basu R, et al.
Eye Vis (Lond)
. 2020 Dec;
7(1):52.
PMID: 33292650
Background: Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent stromal tissue in injured corneas. These effects rely on factors produced by CSSC to block...
7.
Khandaker I, Funderburgh J, Geary M, Funderburgh M, Jhanji V, Du Y, et al.
Exp Eye Res
. 2020 Sep;
200:108270.
PMID: 32979396
Corneal opacities affect vision for millions of individuals worldwide. Fibrotic scar tissues accumulate in reaction to inflammatory responses and remain permanently in corneal stroma, and conventionally correctable only by donor...
8.
Yam G, Riau A, Funderburgh M, Mehta J, Jhanji V
Exp Eye Res
. 2020 May;
196:108062.
PMID: 32442558
The study of corneal stromal keratocytes is motivated by its strong association with corneal health and visual function. They play a dominant role in the maintenance of corneal homeostasis and...
9.
Dos Santos A, Balayan A, Funderburgh M, Ngo J, Funderburgh J, Deng S
Invest Ophthalmol Vis Sci
. 2019 Jul;
60(8):3013-3023.
PMID: 31310658
Purpose: Mesenchymal stem cells (MSCs) have been extensively studied for their capacity to enhance wound healing and represent a promising research field for generating cell therapies for corneal scars. In...
10.
Shojaati G, Khandaker I, Funderburgh M, Mann M, Basu R, Stolz D, et al.
Stem Cells Transl Med
. 2019 Jul;
8(11):1192-1201.
PMID: 31290598
Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring and stimulate regeneration of transparent stromal tissue after corneal wounding in mice. These effects rely on the ability...