Martha D Wilson
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Explore the profile of Martha D Wilson including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Zhang J, Kelley K, Marshall S, Davis M, Wilson M, Sawyer J, et al.
J Lipid Res
. 2012 Mar;
53(6):1144-52.
PMID: 22460046
Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) generates cholesterol esters (CE) for packaging into newly synthesized lipoproteins and thus is a major determinant of blood cholesterol levels. ACAT2 is expressed exclusively in the...
12.
Forrest L, Boudyguina E, Wilson M, Parks J
Atherosclerosis
. 2011 Nov;
220(1):118-21.
PMID: 22100249
Introduction: The anti-atherogenic and hypotriglyceridemic properties of fish oil are attributed to its enrichment in eicosapentaenoic acid (EPA; 20:5, n-3) and docosahexaenoic acid (DHA; 22:6, n-3). Echium oil contains stearidonic...
13.
Sun H, Hu Y, Gu Z, Wilson M, Chen Y, Rudel L, et al.
PLoS One
. 2011 Jun;
6(5):e20502.
PMID: 21655218
Long chain n-3 PUFA have been shown to have chemopreventive properties against breast cancer through various mechanisms. One pathway, studied in human breast cancer cell lines, involves upregulation of the...
14.
Brown J, Betters J, Lord C, Ma Y, Han X, Yang K, et al.
J Lipid Res
. 2010 Aug;
51(11):3306-15.
PMID: 20802159
Mutations of Comparative Gene Identification-58 (CGI-58) in humans cause triglyceride (TG) accumulation in multiple tissues. Mice genetically lacking CGI-58 die shortly after birth due to a skin barrier defect. To...
15.
Zhu X, Owen J, Wilson M, Li H, Griffiths G, Thomas M, et al.
J Lipid Res
. 2010 Jul;
51(11):3196-206.
PMID: 20650929
We previously showed that macrophages from macrophage-specific ATP-binding cassette transporter A1 (ABCA1) knockout (Abca1(-M/-M)) mice had an enhanced proinflammatory response to the Toll-like receptor (TLR) 4 agonist, lipopolysaccharide (LPS), compared...
16.
Kavanagh K, Sajadian S, Jenkins K, Wilson M, Carr J, Wagner J, et al.
Nutr Res
. 2010 Jul;
30(6):418-26.
PMID: 20650350
Industrially produced trans-fatty acids (TFAs) consumed in Western diets are incorporated into maternal and fetal tissues and are passed linearly to offspring via breast milk. We hypothesized that TFA exposure...
17.
Madenspacher J, Draper D, Smoak K, Li H, Griffiths G, Suratt B, et al.
J Immunol
. 2010 Jun;
185(3):1660-9.
PMID: 20581153
Dyslipidemia influences innate immune responses in the bloodstream, but whether and how pulmonary innate immunity is sensitive to circulating lipoproteins is largely unknown. To define whether dyslipidemia impacts responses to...
18.
Alger H, Brown J, Sawyer J, Kelley K, Shah R, Wilson M, et al.
J Biol Chem
. 2010 Mar;
285(19):14267-74.
PMID: 20231283
Acyl-CoA:cholesterol O-acyl transferase 2 (ACAT2) promotes cholesterol absorption by the intestine and the secretion of cholesteryl ester-enriched very low density lipoproteins by the liver. Paradoxically, mice lacking ACAT2 also exhibit...
19.
Degirolamo C, Kelley K, Wilson M, Rudel L
J Lipid Res
. 2010 Feb;
51(7):1897-905.
PMID: 20154006
The atheroprotective potential of n-3 alpha-linolenic acid (ALA) has not yet been fully determined, even in murine models of atherosclerosis. We tested whether ALA-derived, n-3 long chain polyunsaturated fatty acids...
20.
Brown J, Chung S, Sawyer J, Degirolamo C, Alger H, Nguyen T, et al.
Arterioscler Thromb Vasc Biol
. 2009 Oct;
30(1):24-30.
PMID: 19834103
Background: Stearoyl-CoA desaturase 1 (SCD1) is a critical regulator of energy metabolism and inflammation. We have previously reported that inhibition of SCD1 in hyperlipidemic mice fed a saturated fatty acid...