Marlene Bouvier
Overview
Explore the profile of Marlene Bouvier including associated specialties, affiliations and a list of published articles.
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30
Citations
662
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Recent Articles
1.
Macandog A, Catozzi C, Capone M, Nabinejad A, Nanaware P, Liu S, et al.
Cell Host Microbe
. 2024 Oct;
32(11):2004-2018.e9.
PMID: 39481388
Immune checkpoint inhibitors (ICIs) improve outcomes in advanced melanoma, but many patients are refractory or experience relapse. The gut microbiota modulates antitumor responses. However, inconsistent baseline predictors point to heterogeneity...
2.
Li L, Peng X, Batliwala M, Bouvier M
Nat Commun
. 2023 Aug;
14(1):5020.
PMID: 37596268
Studies have suggested that MHC class I (MHC I) molecules fluctuate rapidly between numerous conformational states and these motions support peptide sampling. To date, MHC I intermediates are largely uncharacterized...
3.
Li L, Peng X, Batliwala M, Bouvier M
Res Sq
. 2023 Feb;
PMID: 36747752
Studies have suggested that MHC class I (MHC I) molecules fluctuate rapidly between conformational states as they sample peptides for potential ligands. To date, MHC I intermediates are largely uncharacterized...
4.
Vinjamuri S, Li L, Bouvier M
Front Immunol
. 2022 Nov;
13:1035559.
PMID: 36353628
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. The genome of SARS-CoV-2 encodes nine accessory proteins that are involved in host-pathogen interaction. ORF8 is unique among these accessory proteins....
5.
Camberlein V, Fleau C, Sierocki P, Li L, Gealageas R, Bosc D, et al.
Angew Chem Int Ed Engl
. 2022 Jul;
61(39):e202203560.
PMID: 35904863
Endoplasmic reticulum aminopeptidase 2 (ERAP2) is a key enzyme involved in the trimming of antigenic peptides presented by Major Histocompatibility Complex class I. It is a target of growing interest...
6.
Oliveira E, Li L, Bouvier M
Viruses
. 2021 Aug;
13(7).
PMID: 34372495
The enteric human adenoviruses of species F (HAdVs-F), which comprise HAdV-F40 and HAdV-F41, are significant pathogens that cause acute gastroenteritis in children worldwide. The early transcription unit 3 (E3) of...
7.
Oliveira E, Bouvier M
FEBS Lett
. 2019 Nov;
593(24):3496-3503.
PMID: 31736048
Human adenoviruses (HAdVs) are widespread pathogens that cause a number of partially overlapping, species-specific infections associated with respiratory, urinary, gastrointestinal, and ocular diseases. The early 3 (E3) region of adenoviruses...
8.
Li L, Batliwala M, Bouvier M
J Biol Chem
. 2019 Oct;
294(49):18534-18544.
PMID: 31601650
Endoplasmic reticulum aminopeptidase 1 (ERAP1) and ERAP2 critically shape the major histocompatibility complex I (MHC I) immunopeptidome. The ERAPs remove N-terminal residues from antigenic precursor peptides and generate optimal-length peptides...
9.
Bouvier M
Methods Mol Biol
. 2019 Jun;
1988:71-81.
PMID: 31147933
In the endoplasmic reticulum (ER), MHC class I molecules associate with several specialized proteins, forming a large macromolecular complex referred to as the "peptide-loading complex" (PLC). In the PLC, antigenic...
10.
Weimershaus M, Evnouchidou I, Li L, van Endert P, Bouvier M
Methods Mol Biol
. 2019 Jun;
1988:31-43.
PMID: 31147930
Studies over the last decade on characterization of the major histocompatibility complex (MHC) class I antigen presentation pathway have highlighted the importance of antigen processing, peptide transport, peptide trimming, and...