Mark Ziemann
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Explore the profile of Mark Ziemann including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Wu W, Huynh K, Du J, She G, Duong T, Ziemann M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2024 Dec;
1870(2):159590.
PMID: 39709046
Metabolic reprogramming occurs in cardiomyopathy and heart failure contributing to progression of the disease. Activation of cardiac Hippo pathway signaling has been implicated in mediating mitochondrial dysfunction and metabolic reprogramming...
2.
Lynskey S, Gill S, McGee S, Ziemann M, Page R
BMC Res Notes
. 2024 Dec;
17(1):361.
PMID: 39702481
Objective: Osteoarthritis (OA) is a disease impacting the synovial joint complex, yet transcriptional changes specific to shoulder OA remain underexplored. This study aims to profile transcriptomic changes in periarticular tissues...
3.
Silver J, Trewin A, Loke S, Croft L, Ziemann M, Soria M, et al.
FASEB J
. 2024 Dec;
38(23):e70223.
PMID: 39625361
Mitochondria are central to cellular function, particularly in metabolically active tissues such as skeletal muscle. Nuclear-encoded RNAs typically localize within the nucleus and cytosol but a small population may also...
4.
Ziemann M, Schroeter B, Bora A
Bioinform Adv
. 2024 Nov;
4(1):vbae159.
PMID: 39539946
Motivation: Overrepresentation analysis (ORA) is used widely to assess the enrichment of functional categories in a gene list compared to a background list. ORA is therefore a critical method in...
5.
Bastawy E, Eraslan I, Voglsanger L, Suphioglu C, Walker A, Dean O, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000495
Patients with asthma experience elevated rates of mental illness. However, the molecular links underlying such lung-brain crosstalk remain ambiguous. Hypothalamic dysfunction is observed in many psychiatric disorders, particularly those with...
6.
Ziemann M, Abeysooriya M, Bora A, Lamon S, Kasu M, Norris M, et al.
Epigenetics
. 2024 Jul;
19(1):2375022.
PMID: 38967555
Infinium Methylation BeadChip arrays remain one of the most popular platforms for epigenome-wide association studies, but tools for downstream pathway analysis have their limitations. Functional class scoring (FCS) is a...
7.
Kharel A, Rookes J, Ziemann M, Cahill D
Protoplasma
. 2024 May;
261(5):1073-1092.
PMID: 38702562
Phytophthora cinnamomi is an oomycete plant pathogen with a host range of almost 5000 plant species worldwide and therefore poses a serious threat to biodiversity. Omics technology has provided significant...
8.
Hall L, Czeczor J, Connor T, Botella J, De Jong K, Renton M, et al.
Nat Commun
. 2024 Jan;
15(1):258.
PMID: 38225272
There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer's disease. The role of amyloid beta 42 (Aβ) in these diverse chronic diseases is obscure. Here...
9.
Ziemann M, Poulain P, Bora A
Brief Bioinform
. 2023 Oct;
24(6).
PMID: 37870287
Computational reproducibility is a simple premise in theory, but is difficult to achieve in practice. Building upon past efforts and proposals to maximize reproducibility and rigor in bioinformatics, we present...
10.
Zhang J, Peng Z, Chen K, Zhan Z, Shen H, Feng S, et al.
Microbiol Spectr
. 2023 Jan;
11(1):e0354222.
PMID: 36651774
Salmonella Weltevreden is an emerging pathogen associated with human diarrhea, and knowledge of the genomics and epidemiology of this serovar is still limited. In this study, we performed whole-genome sequencing...