Xiao-Jun Du
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Explore the profile of Xiao-Jun Du including associated specialties, affiliations and a list of published articles.
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Articles
170
Citations
4736
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Recent Articles
1.
Wu W, Huynh K, Du J, She G, Duong T, Ziemann M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2024 Dec;
1870(2):159590.
PMID: 39709046
Metabolic reprogramming occurs in cardiomyopathy and heart failure contributing to progression of the disease. Activation of cardiac Hippo pathway signaling has been implicated in mediating mitochondrial dysfunction and metabolic reprogramming...
2.
Du X, Feng X, Ming Z, Kiriazis H
Physiol Rep
. 2024 Oct;
12(20):e70061.
PMID: 39411804
Correlation between echocardiographic and pathoanatomic variables and their prognostic value in murine cardiomyopathy models remain unknown. Using echocardiography, morphometrics, and survival monitoring, we characterized transgenic (TG) mice with dilated cardiomyopathy...
3.
Du X, She G, Wu W, Deng X
Mitochondrion
. 2024 Aug;
78:101941.
PMID: 39122227
Activation of the sympatho-β-adrenergic receptor (βAR) system is the hallmark of heart disease with adverse consequences that facilitate the onset and progression of heart failure (HF). Use of β-blocking drugs...
4.
Zhang Y, Li J, Xu R, Wang X, Zhao X, Fang Y, et al.
Redox Biol
. 2023 Oct;
68:102944.
PMID: 37890359
Aims: Endothelial dysfunction plays a pivotal role in atherosclerosis, but the detailed mechanism remains incomplete understood. Nogo-B is an endoplasmic reticulum (ER)-localized protein mediating ER-mitochondrial morphology. We previously showed endothelial...
5.
Wang H, Du X, Zhang Y, Xiao H
Sci Bull (Beijing)
. 2023 Oct;
68(22):2704-2708.
PMID: 37884427
No abstract available.
6.
Zhang Y, Ma X, Zhao X, Li J, Ma S, Pang Z, et al.
Heliyon
. 2023 Apr;
9(4):e14823.
PMID: 37025887
Type 2 diabetes mellitus (T2DM) is characterized by chronic low-grade systemic inflammation. Tissue infiltration by monocyte migration contributes to the pathogenesis of vascular complications in T2DM. We studied the role...
7.
Li J, Zhao X, Wang Y, Xu R, Di X, Zhang Y, et al.
Arterioscler Thromb Vasc Biol
. 2023 Mar;
43(5):726-738.
PMID: 36951065
Background: S1P (sphingosine-1-phosphate) has been reported to possess vasodilatory properties, but the underlying pathways are largely unknown. Methods: Isolated mouse mesenteric artery and endothelial cell models were used to determine...
8.
Wu W, Lu Q, Ma S, Du J, Huynh K, Duong T, et al.
Am J Physiol Heart Circ Physiol
. 2023 Mar;
324(4):H528-H541.
PMID: 36867446
Takotsubo syndrome (TTS) is characterized by short-term contractile dysfunction with its mechanism undefined. We showed that activation of cardiac Hippo pathway mediates mitochondrial dysfunction and that stimulation of β-adrenoceptors (βAR)...
9.
Pu T, Wu W, Liang P, Du J, Han S, Deng X, et al.
J Cardiovasc Pharmacol
. 2023 Jan;
81(4):259-269.
PMID: 36668724
Mitochondrial dysfunction plays a key role in the development of heart failure, but targeted therapeutic interventions remain elusive. Previous studies have shown coenzyme Q10 (CoQ10) insufficiency in patients with heart...
10.
She G, Du J, Wu W, Pu T, Zhang Y, Bai R, et al.
Theranostics
. 2023 Jan;
13(2):560-577.
PMID: 36632235
Chemotherapy is a common clinical strategy for cancer treatment. However, the accompanied cardiomyopathy renders cancer patients under risk of another life-threatening condition. Whereas Hippo pathway is known to play key...