Geert Stange
Overview
Explore the profile of Geert Stange including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1697
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0
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Recent Articles
1.
Van Hulle F, De Groot K, Hilbrands R, Van de Velde U, Suenens K, Stange G, et al.
Am J Transplant
. 2021 Nov;
22(3):927-936.
PMID: 34735732
Intraportal (IP) islet cell transplants can restore metabolic control in type 1 diabetes patients, but limitations raise the need for establishing a functional beta cell mass (FBM) in a confined...
2.
Martens G, Stange G, Piemonti L, Anckaert J, Ling Z, Pipeleers D, et al.
Cells
. 2021 Aug;
10(7).
PMID: 34359863
Ongoing beta cell death in type 1 diabetes (T1D) can be detected using biomarkers selectively discharged by dying beta cells into plasma. microRNA-375 (miR-375) ranks among the top biomarkers based...
3.
Smeets S, De Paep D, Stange G, Verhaeghen K, Van der Auwera B, Keymeulen B, et al.
Virchows Arch
. 2021 Feb;
479(2):295-304.
PMID: 33594586
Autoantibodies against islet cell antigens are routinely used to identify subjects at increased risk of symptomatic type 1 diabetes, but their relation to the intra-islet pathogenetic process that leads to...
4.
Van Hulle F, De Groot K, Stange G, Suenens K, De Mesmaeker I, De Paep D, et al.
Am J Transplant
. 2020 Nov;
21(6):2090-2099.
PMID: 33206461
Detection of amyloid in intraportal islet implants of type 1 diabetes patients has been proposed as cause in their functional decline. The present study uses cultured adult human islets devoid...
5.
Smeets S, Staels W, Stange G, Gillard P, De Leu N, Int Veld P
Virchows Arch
. 2020 Aug;
478(6):1209-1214.
PMID: 32833039
Insulitis is a characteristic inflammatory lesion consisting of immune cell infiltrates around and within the pancreatic islets of patients with recent-onset type 1 diabetes (T1D). The infiltration is typically mild,...
6.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stange G, et al.
Nat Biotechnol
. 2020 Feb;
38(3):374.
PMID: 32066957
This article has been retracted; see accompanying Retraction Note, which can be accessed via a link at the top of the paper.
7.
Evidence of Tissue Repair in Human Donor Pancreas After Prolonged Duration of Stay in Intensive Care
Smeets S, Stange G, Leuckx G, Roelants L, Cools W, De Paep D, et al.
Diabetes
. 2019 Dec;
69(3):401-412.
PMID: 31843955
M2 macrophages play an important role in tissue repair and regeneration. They have also been found to modulate β-cell replication in mouse models of pancreatic injury and disease. We previously...
8.
Bolli E, DHuyvetter M, Murgaski A, Berus D, Stange G, Clappaert E, et al.
J Control Release
. 2019 Oct;
314:1-11.
PMID: 31626860
Radioimmunotherapy (RIT) aims to deliver a high radiation dose to cancer cells, while minimizing the exposure of normal cells. Typically, monoclonal antibodies are used to target the radionuclides to cancer...
9.
Akbib S, Stichelmans J, Stange G, Ling Z, Assefa Z, Hellemans K
PLoS One
. 2019 Feb;
14(2):e0212210.
PMID: 30779812
Cell therapy for diabetes could benefit from the identification of small-molecule compounds that increase the number of functional pancreatic beta cells. Using a newly developed screening assay, we previously identified...
10.
Roels S, Costa O, Tersey S, Stange G, De Smet D, Balti E, et al.
J Clin Endocrinol Metab
. 2018 Sep;
104(2):451-460.
PMID: 30203041
Aim: Several biomarkers have been proposed to detect pancreatic β cell destruction in vivo but so far have not been compared for sensitivity and significance. Methods: We used islet transplantation...