Mark S Rybchyn
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Explore the profile of Mark S Rybchyn including associated specialties, affiliations and a list of published articles.
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22
Citations
424
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Recent Articles
1.
Goswami A, Rybchyn M, Walsh W, le Coutre J
Heliyon
. 2024 Oct;
10(18):e38006.
PMID: 39364244
Cellular Agriculture (CellAg) is an attractive concept for innovative technology with the intent to provide food and nutrition complementary to existing supply streams. The past decade has seen considerable progress...
2.
Chaves A, Rybchyn M, Mason R, Fraser D
Comp Biochem Physiol A Mol Integr Physiol
. 2024 May;
295:111666.
PMID: 38763476
The origin of vitamin D in herbivorous animals was investigated in vivo in sheep and in bovine as well as mouse gastrointestinal tracts. A high concentration of 25-hydroxyvitamin D in...
3.
Shariev A, Painter N, Reeve V, Haass N, Rybchyn M, Ince F, et al.
J Steroid Biochem Mol Biol
. 2022 Jan;
218:106059.
PMID: 35033661
Melanoma is the most dangerous form of skin cancer, with poor prognosis in advanced stages. Vitamin D, also produced by ultraviolet radiation, is known for its anti-proliferative properties in some...
4.
Rybchyn M, Biazik J, Charlesworth J, le Coutre J
ACS Omega
. 2021 Dec;
6(49):33923-33931.
PMID: 34926939
The three-dimensional formation of bio-engineered tissue for applications such as cell-based meat requires critical interaction between the bioscaffold and cellular biomass. To explore the features underlying this interaction, we have...
5.
Rybchyn M, Brennan-Speranza T, Mor D, Cheng Z, Chang W, Conigrave A, et al.
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34204449
We recently found that, in human osteoblasts, Homer1 complexes to Calcium-sensing receptor (CaSR) and mediates AKT initiation via mechanistic target of rapamycin complex (mTOR) complex 2 (mTORC2) leading to beneficial...
6.
Ross D, Yeh T, King S, Mathers J, Rybchyn M, Neist E, et al.
Nutrients
. 2021 Jun;
13(5).
PMID: 34068953
Increased risks of skeletal fractures are common in patients with impaired glucose handling and type 2 diabetes mellitus (T2DM). The pathogenesis of skeletal fragility in these patients remains ill-defined as...
7.
Tongkao-On W, Yang C, McCarthy B, De Silva W, Rybchyn M, Gordon-Thomson C, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33669452
Susceptibility to photoimmune suppression and photocarcinogenesis is greater in male than in female humans and mice and is exacerbated in female estrogen receptor-beta knockout (ER-β-/-) mice. We previously reported that...
8.
Mason R, Rybchyn M, Brennan-Speranza T, Fraser D
Fac Rev
. 2021 Mar;
9:19.
PMID: 33659951
Severe vitamin D deficiency-25-hydroxyvitamin D (25OHD) concentrations below around 25-30 nmol/L-may lead to growth plate disorganization and mineralization abnormalities in children (rickets) and mineralization defects throughout the skeleton (osteomalacia) and...
9.
Rybchyn M, Abboud M, Puglisi D, Gordon-Thomson C, Brennan-Speranza T, Mason R, et al.
Nutrients
. 2020 Oct;
12(11).
PMID: 33114526
Vitamin D, unlike the micronutrients, vitamins A, E, and K, is largely obtained not from food, but by the action of solar ultraviolet (UV) light on its precursor, 7-dehydrocholesterol, in...
10.
De Silva W, Abboud M, Yang C, Dixon K, Rybchyn M, Mason R
Adv Exp Med Biol
. 2020 Sep;
1268:227-253.
PMID: 32918222
Exposure of skin cells to UV radiation results in DNA damage, which if inadequately repaired, may cause mutations. UV-induced DNA damage and reactive oxygen and nitrogen species also cause local...