Mark P de Caestecker
Overview
Explore the profile of Mark P de Caestecker including associated specialties, affiliations and a list of published articles.
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48
Citations
1013
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Recent Articles
1.
Vanichapol T, Gonzalez A, Delgado R, Brewer M, Clouthier K, Menshikh A, et al.
JCI Insight
. 2025 Jan;
10(5).
PMID: 39847447
Urinary obstruction causes injury to the renal medulla, impairing the ability to concentrate urine and increasing the risk of progressive kidney disease. However, the regenerative capacity of the renal medulla...
2.
Brewer M, Migas L, Clouthier K, Allen J, Anderson D, Pingry E, et al.
Am J Physiol Renal Physiol
. 2024 May;
327(1):F91-F102.
PMID: 38721662
The lack of standardization in antibody validation remains a major contributor to irreproducibility of human research. To address this, we have applied a standardized approach to validate a panel of...
3.
Kimlinger M, No T, Mace E, Delgado R, Lopez M, de Caestecker M, et al.
Anesth Analg
. 2023 Sep;
137(5):996-1006.
PMID: 37678264
Background: Renal ischemia and reperfusion (IR) contribute to perioperative acute kidney injury, and oxygen is a key regulator of this process. We hypothesized that oxygen administration during surgery and renal...
4.
Hernandez A, Patil N, Brewer M, Delgado R, Himmel L, Lopez L, et al.
Am J Physiol Renal Physiol
. 2023 Mar;
324(5):F472-F482.
PMID: 36995924
Acute kidney injury (AKI) is common in surgical and critically ill patients. This study examined whether pretreatment with a novel Toll-like receptor 4 agonist attenuated ischemia-reperfusion injury (IRI)-induced AKI (IRI-AKI)....
5.
Lee H, Tang Y, Bao S, Yang Q, Xu X, Fogo A, et al.
Proc SPIE Int Soc Opt Eng
. 2022 Oct;
12032.
PMID: 36303577
The Human BioMolecular Atlas Program (HuBMAP) provides an opportunity to contextualize findings across cellular to organ systems levels. Constructing an atlas target is the primary endpoint for generalizing anatomical information...
6.
Wang F, Otsuka T, Adelnia F, Takahashi K, Delgado R, Harkins K, et al.
NMR Biomed
. 2022 Jun;
35(10):e4786.
PMID: 35704387
Tubular atrophy and fibrosis are pathological changes that determine the prognosis of kidney disease induced by acute kidney injury (AKI). We aimed to evaluate multiple magnetic resonance imaging (MRI) parameters,...
7.
Lee H, Tang Y, Xu K, Bao S, Fogo A, Harris R, et al.
Comput Biol Med
. 2022 May;
146:105555.
PMID: 35533459
The construction of three-dimensional multi-modal tissue maps provides an opportunity to spur interdisciplinary innovations across temporal and spatial scales through information integration. While the preponderance of effort is allocated to...
8.
Naved B, Bonventre J, Hubbell J, Hukriede N, Humphreys B, Kesselman C, et al.
Kidney Int
. 2022 Mar;
101(5):845-853.
PMID: 35276204
Acute kidney injury impacts ∼13.3 million individuals and causes ∼1.7 million deaths per year globally. Numerous injury pathways contribute to acute kidney injury, including cell cycle arrest, senescence, inflammation, mitochondrial...
9.
Hukriede N, Soranno D, Sander V, Perreau T, Starr M, Yuen P, et al.
Nat Rev Nephrol
. 2022 Feb;
18(5):277-293.
PMID: 35173348
Preclinical models of human disease provide powerful tools for therapeutic discovery but have limitations. This problem is especially apparent in the field of acute kidney injury (AKI), in which clinical...
10.
Tang Y, Gao R, Lee H, Xu Z, Savoie B, Bao S, et al.
Proc SPIE Int Soc Opt Eng
. 2021 Sep;
11596.
PMID: 34531632
Renal segmentation on contrast-enhanced computed tomography (CT) provides distinct spatial context and morphology. Current studies for renal segmentations are highly dependent on manual efforts, which are time-consuming and tedious. Hence,...