Mark N Read
Overview
Explore the profile of Mark N Read including associated specialties, affiliations and a list of published articles.
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15
Citations
396
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Recent Articles
1.
Putri G, Chung J, Edwards D, Marsh-Wakefield F, Koprinska I, Dervish S, et al.
Cytometry A
. 2022 Jun;
103(1):54-70.
PMID: 35758217
Mapping the dynamics of immune cell populations over time or disease-course is key to understanding immunopathogenesis and devising putative interventions. We present TrackSOM, a novel method for delineating cellular populations...
2.
Marsh-Wakefield F, Juillard P, Ashhurst T, Juillard A, Shinko D, Putri G, et al.
Immunol Cell Biol
. 2022 Apr;
100(6):453-467.
PMID: 35416319
B cells play a major role in multiple sclerosis (MS), with many successful therapeutics capable of removing them from circulation. One such therapy, alemtuzumab, is thought to reset the immune...
3.
Molina Ortiz J, McClure D, Shanahan E, Dehghani F, Holmes A, Read M
Gut Microbes
. 2021 Aug;
13(1):1965698.
PMID: 34455914
The gut microbiome has emerged as a contributing factor in non-communicable disease, rendering it a target of health-promoting interventions. Yet current understanding of the host-microbiome dynamic is insufficient to predict...
4.
Hywood J, Rice G, Pageon S, Read M, Biro M
J R Soc Interface
. 2021 Mar;
18(176):20200879.
PMID: 33715400
Swarming has been observed in various biological systems from collective animal movements to immune cells. In the cellular context, swarming is driven by the secretion of chemotactic factors. Despite the...
5.
Koutsakos M, Rowntree L, Hensen L, Chua B, van de Sandt C, Habel J, et al.
Cell Rep Med
. 2021 Feb;
2(3):100208.
PMID: 33564749
SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or convalescent time points, up to 102 days...
6.
Putri G, Koprinska I, Ashhurst T, King N, Read M
Bioinformatics
. 2021 Jan;
PMID: 33508103
Motivation: Many 'automated gating' algorithms now exist to cluster cytometry and single cell sequencing data into discrete populations. Comparative algorithm evaluations on benchmark datasets rely either on a single performance...
7.
Lamm N, Read M, Nobis M, Van Ly D, Page S, Masamsetti V, et al.
Nat Cell Biol
. 2020 Dec;
22(12):1460-1470.
PMID: 33257806
Filamentous actin (F-actin) provides cells with mechanical support and promotes the mobility of intracellular structures. Although F-actin is traditionally considered to be cytoplasmic, here we reveal that nuclear F-actin participates...
8.
Galeano Nino J, Pageon S, Tay S, Colakoglu F, Kempe D, Hywood J, et al.
Elife
. 2020 Oct;
9.
PMID: 33046212
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations...
9.
Zoll J, Read M, Heywood S, Estevez E, Marshall J, Kammoun H, et al.
Am J Physiol Endocrinol Metab
. 2020 Jun;
319(1):E203-E216.
PMID: 32516027
Studies suggest the gut microbiota contributes to the development of obesity and metabolic syndrome. Exercise alters microbiota composition and diversity and is protective of these maladies. We tested whether the...
10.
Read M, Alden K, Timmis J, Andrews P
Brief Bioinform
. 2018 Sep;
21(1):24-35.
PMID: 30239570
Computational and mathematical modelling has become a valuable tool for investigating biological systems. Modelling enables prediction of how biological components interact to deliver system-level properties and extrapolation of biological system...