» Authors » Marjan Slak Rupnik

Marjan Slak Rupnik

Explore the profile of Marjan Slak Rupnik including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 51
Citations 1009
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Rizk A, Dybala M, Rodriguez K, Rupnik M, Hara M
J Clin Invest . 2023 Jun; 133(15). PMID: 37338995
An increasing number of studies have demonstrated that disease states of the endocrine or exocrine pancreas aggravate one another, which implies bidirectional blood flow between islets and exocrine cells. However,...
12.
Postic S, Pfabe J, Sarikas S, Ehall B, Pieber T, Korosak D, et al.
Diabetes . 2023 May; 72(9):1251-1261. PMID: 37257067
Article Highlights: In NOD mice β-cells, 8 mmol/L glucose-induced synchronized short [Ca2+]c events diminish in the early phases of islet inflammation, and long Ca2+ events became more sensitive to substimulatory...
13.
Sterk M, Dolensek J, Klemen M, Krizancic Bombek L, Leitgeb E, Kercmar J, et al.
Biophys J . 2023 Feb; 122(5):784-801. PMID: 36738106
Islets of Langerhans operate as multicellular networks in which several hundred β cells work in synchrony to produce secretory pulses of insulin, a hormone crucial for controlling metabolic homeostasis. Their...
14.
Postic S, Sarikas S, Pfabe J, Pohorec V, Krizancic Bombek L, Sluga N, et al.
Am J Physiol Endocrinol Metab . 2022 Nov; 324(1):E42-E55. PMID: 36449570
The release of peptide hormones is predominantly regulated by a transient increase in cytosolic Ca concentration ([Ca]). To trigger exocytosis, Ca ions enter the cytosol from intracellular Ca stores or...
15.
Sluga N, Krizancic Bombek L, Kercmar J, Sarikas S, Postic S, Pfabe J, et al.
Front Endocrinol (Lausanne) . 2022 Nov; 13:1013697. PMID: 36387857
Adrenaline inhibits insulin secretion from pancreatic beta cells to allow an organism to cover immediate energy needs by unlocking internal nutrient reserves. The stimulation of α2-adrenergic receptors on the plasma...
16.
Postic S, Gosak M, Tsai W, Pfabe J, Sarikas S, Stozer A, et al.
Front Endocrinol (Lausanne) . 2022 Jul; 13:916688. PMID: 35837307
Extracellular pH has the potential to affect various aspects of the pancreatic beta cell function. To explain this effect, a number of mechanisms was proposed involving both extracellular and intracellular...
17.
Tsai W, Grauffel C, Huang M, Postic S, Rupnik M, Lim C, et al.
J Biol Chem . 2022 May; 298(6):101998. PMID: 35500647
Opening of two-pore domain K channels (K2Ps) is regulated by various external cues, such as pH, membrane tension, or temperature, which allosterically modulate the selectivity filter (SF) gate. However, how...
18.
Korosak D, Jusup M, Podobnik B, Stozer A, Dolensek J, Holme P, et al.
Phys Rev Lett . 2021 Nov; 127(16):168101. PMID: 34723613
β cells are biologically essential for humans and other vertebrates. Because their functionality arises from cell-cell interactions, they are also a model system for collective organization among cells. There are...
19.
Stozer A, Klemen M, Gosak M, Krizancic Bombek L, Pohorec V, Rupnik M, et al.
Am J Physiol Endocrinol Metab . 2021 Jul; 321(2):E305-E323. PMID: 34280052
Many details of glucose-stimulated intracellular calcium changes in β cells during activation, activity, and deactivation, as well as their concentration-dependence, remain to be analyzed. Classical physiological experiments indicated that in...
20.
Sluga N, Postic S, Sarikas S, Huang Y, Stozer A, Rupnik M
Cells . 2021 Jul; 10(7). PMID: 34201461
Cholinergic innervation in the pancreas controls both the release of digestive enzymes to support the intestinal digestion and absorption, as well as insulin release to promote nutrient use in the...