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Marit Westerterp

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Articles 92
Citations 3468
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Recent Articles
1.
Halmos B, La Rose A, Methorst D, Groenen A, Nakladal D, Bazioti V, et al.
Circ Res . 2025 Feb; 136(5):491-507. PMID: 39931819
Background: Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by α-ARs (α-adrenergic receptors). Plasma membrane cholesterol accumulation affects α-AR signaling and promotes loss of SMC contractile markers...
2.
Renkens M, Coerkamp C, Witte L, Sivanesan S, Nurmohamed N, Westerterp M, et al.
Expert Rev Cardiovasc Ther . 2024 Sep; 22(8):353-366. PMID: 39258965
Introduction: Lipoprotein(a) [Lp(a)] is linked to higher risks of atherosclerotic cardiovascular disease (ASCVD). Current guideline recommendations are quite liberal on measuring Lp(a) (Class IIa, Level C), and may lead to...
3.
Groenen A, Lipscomb M, Ramos R, Sadhu S, Bazioti V, Fredman G, et al.
Prostaglandins Leukot Essent Fatty Acids . 2024 Aug; 202:102634. PMID: 39167848
Aging is associated with systemic, non-resolving inflammation and the accumulation of senescent cells. The resolution of inflammation (or inflammation-resolution) is in part mediated by the balance between specialized pro-resolving mediators...
4.
Groenen A, Halmos B, van Zeventer I, Salzbrunn J, Mayer M, La Rose N, et al.
Atherosclerosis . 2024 Jun; 395:117609. PMID: 38878675
Background And Aims: Previous studies have shown that skin autofluorescence (SAF), measured with an advanced glycation end product (AGE) reader, estimates the accumulation of AGEs in tissues. SAF is predictive...
5.
Yalcinkaya M, Liu W, Xiao T, Abramowicz S, Wang R, Wang N, et al.
J Lipid Res . 2024 Mar; 65(4):100534. PMID: 38522750
The deposition of cholesterol-rich lipoproteins in the arterial wall triggers macrophage inflammatory responses, which promote atherosclerosis. The NLRP3 inflammasome aggravates atherosclerosis; however, cellular mechanisms connecting macrophage cholesterol accumulation to inflammasome...
6.
Groenen A, Matveyenko A, Matienzo N, Halmos B, Zhang H, Westerterp M, et al.
Atherosclerosis . 2024 Mar; 391:117474. PMID: 38428286
Background And Aims: High plasma lipoprotein (a) [Lp(a)] levels are associated with increased atherosclerotic cardiovascular disease (ASCVD), in part attributed to elevated inflammation. High plasma Lp(a) levels inversely correlate with...
7.
Sijbesma J, van Waarde A, Kristensen S, Kion I, Tietge U, Hillebrands J, et al.
EJNMMI Res . 2023 Dec; 13(1):106. PMID: 38079017
Background: The apolipoprotein E-deficient (apoE) mouse is a well-established model for studying atherosclerosis. However, its small size limits its use in longitudinal positron emission tomography (PET) imaging studies. Recently, the...
8.
Westerterp M, Li F, Zhang H
J Lipid Res . 2023 Nov; 64(12):100474. PMID: 37972729
No abstract available.
9.
Yalcinkaya M, Liu W, Thomas L, Olszewska M, Xiao T, Abramowicz S, et al.
Circulation . 2023 Oct; 148(22):1764-1777. PMID: 37781816
Background: Clonal hematopoiesis (CH) has emerged as an independent risk factor for atherosclerotic cardiovascular disease, with activation of macrophage inflammasomes as a potential underlying mechanism. The NLRP3 (NLR family pyrin...
10.
Bazioti V, Halmos B, Westerterp M
Curr Atheroscler Rep . 2023 Jul; 25(9):527-534. PMID: 37395922
Purpose Of Review: The majority of leukocytes in advanced human atherosclerotic plaques are T-cells. T-cell subsets exert pro- or anti-atherogenic effects largely via the cytokines they secrete. T cells (T)...