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Anouk M La Rose

Explore the profile of Anouk M La Rose including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 50
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Recent Articles
1.
Halmos B, La Rose A, Methorst D, Groenen A, Nakladal D, Bazioti V, et al.
Circ Res . 2025 Feb; 136(5):491-507. PMID: 39931819
Background: Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by α-ARs (α-adrenergic receptors). Plasma membrane cholesterol accumulation affects α-AR signaling and promotes loss of SMC contractile markers...
2.
La Rose A, Groenen A, Halmos B, Bazioti V, Rutten M, Krishnamurthy K, et al.
Mol Genet Metab Rep . 2022 Jul; 31:100872. PMID: 35782606
Glycogen storage disease type 1a (GSD Ia) is an inborn error of carbohydrate metabolism. Despite severe hyperlipidemia, GSD Ia patients show limited atherogenesis compared to age-and-gender matched controls. Employing a...
3.
Bazioti V, La Rose A, Maassen S, Bianchi F, de Boer R, Halmos B, et al.
Nat Commun . 2022 Jul; 13(1):3799. PMID: 35778407
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect of cholesterol efflux pathways mediated by ATP-binding cassette A1...
4.
Groenen A, La Rose A, Li M, Bazioti V, Svendsen A, Kloosterhuis N, et al.
J Lipid Res . 2022 Jan; 63(2):100167. PMID: 35007562
Niemann-Pick type C1 (NPC1) disease is a progressive lysosomal storage disorder caused by mutations of the NPC1 gene. While neurodegeneration is the most severe symptom, a large proportion of NPC1...
5.
La Rose A, Bazioti V, Hoogerland J, Svendsen A, Groenen A, van Faassen M, et al.
Mol Metab . 2021 Jun; 53:101265. PMID: 34091064
Objective: Glycogen storage disease type 1a (GSD Ia) is a rare inherited metabolic disorder caused by mutations in the glucose-6-phosphatase (G6PC1) gene. When untreated, GSD Ia leads to severe fasting-induced...
6.
de Boer J, de Vries H, Palmiotti A, Li R, Doestzada M, Hoogerland J, et al.
Cell Mol Gastroenterol Hepatol . 2020 Dec; 11(4):1045-1069. PMID: 33309945
Background And Aims: Bile acids (BAs) aid intestinal fat absorption and exert systemic actions by receptor-mediated signaling. BA receptors have been identified as drug targets for liver diseases. Yet, differences...
7.
Bazioti V, La Rose A, Westerterp M
Curr Opin Lipidol . 2018 Mar; 29(3):233-239. PMID: 29601312
Purpose Of Review: Leukocytosis, elevated blood leukocyte levels, is associated with enhanced cardiovascular risk in humans. Hematopoietic stem and progenitor cells (HSPCs) drive leukocyte production in a process called hematopoiesis,...
8.
La Rose A, Bazioti V, Westerterp M
Arterioscler Thromb Vasc Biol . 2018 Mar; 38(4):687-689. PMID: 29563111
No abstract available.