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Mario Mancino

Explore the profile of Mario Mancino including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1401
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Recent Articles
1.
Llombart-Cussac A, Perez-Garcia J, Braso-Maristany F, Pare L, Villacampa G, Gion M, et al.
Clin Cancer Res . 2024 Jul; 30(18):4123-4130. PMID: 38995291
Purpose: The purpose of this study was to assess the predictive capability of HER2DX assay following (neo)adjuvant trastuzumab-pertuzumab (HP)-based therapy in HER2-positive (HER2+) early breast cancer. Experimental Design: HER2DX was...
2.
Gion M, Garcia-Mosquera J, Perez-Garcia J, Peg V, Ruiz-Borrego M, Stradella A, et al.
Breast Cancer Res Treat . 2024 Mar; 205(3):589-598. PMID: 38456970
Purpose: The prognostic and predictive role of trophoblast cell-surface antigen-2 (Trop-2) overexpression in human epidermal growth factor receptor 2-positive (HER2-positive) breast cancer is currently unknown. We retrospectively analyzed Trop-2 expression...
3.
Herranz C, Mateo F, Baiges A, Ruiz de Garibay G, Junza A, Johnson S, et al.
EMBO Mol Med . 2021 Aug; 13(9):e13929. PMID: 34378323
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis...
4.
Fernandez-Nogueira P, Mancino M, Fuster G, Bragado P, Puig M, Gascon P, et al.
J Clin Med . 2020 Mar; 9(3). PMID: 32178425
Current evidences state clear that both normal development of breast tissue as well as its malignant progression need many-sided local and systemic communications between epithelial cells and stromal components. During...
5.
Lopez-Plana A, Fernandez-Nogueira P, Munoz-Guardiola P, Sole-Sanchez S, Megias-Roda E, Perez-Montoyo H, et al.
Int J Cancer . 2020 Jan; 147(4):1163-1179. PMID: 31943158
Around 40% of newly diagnosed lung cancer patients are Stage IV, where the improvement of survival and reduction of disease-related adverse events is the main goal for oncologists. In this...
6.
Fernandez-Nogueira P, Mancino M, Fuster G, Lopez-Plana A, Jauregui P, Almendro V, et al.
Clin Cancer Res . 2019 Nov; 26(6):1432-1448. PMID: 31699826
Purpose: Despite the therapeutic success of existing HER2-targeted therapies, tumors invariably relapse. This study aimed at identifying new mechanisms responsible for HER2-targeted therapy resistance. Experimental Design: We have used a...
7.
Zubeldia-Plazaola A, Recalde-Percaz L, Moragas N, Alcaraz M, Chen X, Mancino M, et al.
Breast Cancer Res . 2018 Jul; 20(1):65. PMID: 29973218
Background: The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of breast cancer and, particularly, in myoepithelial...
8.
Fernandez-Nogueira P, Noguera-Castells A, Fuster G, Recalde-Percaz L, Moragas N, Lopez-Plana A, et al.
Cancer Lett . 2018 Mar; 424:70-83. PMID: 29548821
Histamine receptor 1 (HRH1) belongs to the rhodopsin-like G-protein-coupled receptor family. Its activation by histamine triggers cell proliferation, embryonic development, and tumor growth. We recently established that HRH1 is up-regulated...
9.
Fernandez-Nogueira P, Bragado P, Almendro V, Ametller E, Rios J, Choudhury S, et al.
Oncotarget . 2015 Dec; 7(5):5313-26. PMID: 26673618
The nervous system is now recognized to be a relevant component of the tumor microenvironment. Receptors for neuropeptides and neurotransmitters have been identified in breast cancer. However, very little is...
10.
Zubeldia-Plazaola A, Ametller E, Mancino M, Puig M, Lopez-Plana A, Guzman F, et al.
Front Cell Dev Biol . 2015 Jun; 3:32. PMID: 26052514
Two lineages, epithelial, and myoepithelial cells are the main cell populations in the normal mammary gland and in breast cancer. Traditionally, cancer research has been performed using commercial cell lines,...