Marianna E Jung
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Explore the profile of Marianna E Jung including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Jung M
Cerebellum
. 2014 Sep;
14(4):421-37.
PMID: 25195804
Cerebellar disorders trigger the symptoms of movement problems, imbalance, incoordination, and frequent fall. Cerebellar disorders are shown in various CNS illnesses including a drinking disorder called alcoholism. Alcoholism is manifested...
12.
Ju X, Mallet R, Downey H, Metzger D, Jung M
J Appl Physiol (1985)
. 2012 Mar;
112(10):1706-14.
PMID: 22403345
Intermittent hypoxia (IH) conditioning minimizes neurocognitive impairment and stabilizes brain mitochondrial integrity during ethanol withdrawal (EW) in rats, but the mitoprotective mechanism is unclear. We investigated whether IH conditioning protects...
13.
Jung M, Ju X, Metzger D, Simpkins J
Neurobiol Aging
. 2011 Mar;
33(3):618.e21-32.
PMID: 21439684
We investigated whether abrupt ethanol withdrawal (EW) age-specifically inhibits a key mitochondrial enzyme, cytochrome c oxidase (COX), and whether estrogen mitigates this problem. We also tested whether this possible effect...
14.
Jung M, Metzger D
Molecules
. 2010 Jul;
15(7):4984-5011.
PMID: 20657404
Unmanaged sudden withdrawal from the excessive consumption of alcohol (ethanol) adversely alters neuronal integrity in vulnerable brain regions such as the cerebellum, hippocampus, or cortex. In addition to well known...
15.
Jung M, Ju X, Simpkins J, Metzger D, Yan L, Wen Y
Neurobiol Aging
. 2010 Feb;
32(12):2266-78.
PMID: 20122756
We investigated whether protein kinase p38 plays a role in the brain-aging changes associated with repeated ethanol withdrawal (EW). Ovariectomized young, middle-age and older rats, with or without 17β-estradiol (E2)...
16.
Prokai-Tatrai K, Prokai L, Simpkins J, Jung M
Int J Mol Sci
. 2009 May;
10(4):1773-1787.
PMID: 19468338
Ethanol withdrawal is linked to elevated oxidative damage to neurons. Here we report our findings on the contribution of phenolic antioxidants (17beta-estradiol, p-octyl-phenol and 2,6-di-tert-butyl-4-methylphenol) to counterbalance sudden ethanol withdrawal-initiated...
17.
Jung M, Wilson A, Ju X, Wen Y, Metzger D, Simpkins J
J Pharmacol Exp Ther
. 2008 Dec;
328(3):692-8.
PMID: 19050172
We have reported that the major endogenous estrogen, 17beta-estradiol (E2), protects against oxidative injury during ethanol withdrawal (EW) in a cultured hippocampal cell line (HT22). Here, we investigated whether the...
18.
Jung M, Simpkins J, Wilson A, Downey H, Mallet R
J Appl Physiol (1985)
. 2008 May;
105(2):510-7.
PMID: 18499779
Intermittent hypoxia (IH) has been found to protect brain from ischemic injury. We investigated whether IH mitigates brain oxidative stress and behavioral deficits in rats subjected to ethanol intoxication and...
19.
Jung M, Yan L, Forster M, Simpkins J
J Bioenerg Biomembr
. 2008 Jan;
40(1):35-44.
PMID: 18210193
We investigated whether ethanol withdrawal (EW) oxidizes mitochondrial proteins and provokes mitochondrial membrane swelling and whether estrogen deprivation contributes to this problem. Ovariectomized female rats with or without 17beta-estradiol (E2)-implantation...
20.
Jung M, Agarwal R, Simpkins J
Neurosci Lett
. 2007 Feb;
416(2):160-4.
PMID: 17320290
Cytochrome c oxidase (COX) is a key mitochondrial enzyme that catalyzes electron transfer at the terminal stage of respiratory chain and is composed of multisubunits. We hypothesize that ethanol withdrawal...