Mariana Justino de Almeida
Overview
Explore the profile of Mariana Justino de Almeida including associated specialties, affiliations and a list of published articles.
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7
Citations
592
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0
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Recent Articles
1.
Corrigan D, Luchsinger L, Justino de Almeida M, Williams L, Strikoudis A, Snoeck H
J Clin Invest
. 2018 Jun;
128(8):3250-3264.
PMID: 29878897
PRDM16 is a transcriptional coregulator involved in translocations in acute myeloblastic leukemia (AML), myelodysplastic syndromes, and T acute lymphoblastic leukemia that is highly expressed in and required for the maintenance...
2.
Justino de Almeida M, Luchsinger L, Corrigan D, Williams L, Snoeck H
Cell Stem Cell
. 2017 Dec;
21(6):725-729.e4.
PMID: 29198942
Hematopoietic stem cells (HSCs) produce most cellular energy through glycolysis rather than through mitochondrial respiration. Consistent with this notion, mitochondrial mass has been reported to be low in HSCs. However,...
3.
Luchsinger L, Justino de Almeida M, Corrigan D, Mumau M, Snoeck H
Nature
. 2016 Jan;
529(7587):528-31.
PMID: 26789249
Haematopoietic stem cells (HSCs), which sustain production of all blood cell lineages, rely on glycolysis for ATP production, yet little attention has been paid to the role of mitochondria. Here...
4.
Petersen I, Gabryszewski S, Johnston G, Dhingra S, Ecker A, Lewis R, et al.
Mol Microbiol
. 2015 Apr;
97(2):381-95.
PMID: 25898991
The widespread use of chloroquine to treat Plasmodium falciparum infections has resulted in the selection and dissemination of variant haplotypes of the primary resistance determinant PfCRT. These haplotypes have encountered...
5.
Stickles A, Justino de Almeida M, Morrisey J, Sheridan K, Forquer I, Nilsen A, et al.
Antimicrob Agents Chemother
. 2015 Jan;
59(4):1977-82.
PMID: 25605352
The cytochrome bc1 complex (cyt bc1) is the third component of the mitochondrial electron transport chain and is the target of several potent antimalarial compounds, including the naphthoquinone atovaquone (ATV)...
6.
Jimenez-Diaz M, Ebert D, Salinas Y, Pradhan A, Lehane A, Myrand-Lapierre M, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(50):E5455-62.
PMID: 25453091
Drug discovery for malaria has been transformed in the last 5 years by the discovery of many new lead compounds identified by phenotypic screening. The process of developing these compounds...
7.
Deng S, Gibb B, Justino de Almeida M, Greene E, Symington L
Nat Struct Mol Biol
. 2014 Mar;
21(4):405-12.
PMID: 24608368
Microhomology-mediated end joining (MMEJ) is a Ku- and ligase IV-independent mechanism for the repair of DNA double-strand breaks that contributes to chromosome rearrangements. Here we used a chromosomal end-joining assay...