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David J Corrigan

Explore the profile of David J Corrigan including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 279
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Recent Articles
1.
Corrigan D, Luchsinger L, Justino de Almeida M, Williams L, Strikoudis A, Snoeck H
J Clin Invest . 2018 Jun; 128(8):3250-3264. PMID: 29878897
PRDM16 is a transcriptional coregulator involved in translocations in acute myeloblastic leukemia (AML), myelodysplastic syndromes, and T acute lymphoblastic leukemia that is highly expressed in and required for the maintenance...
2.
Justino de Almeida M, Luchsinger L, Corrigan D, Williams L, Snoeck H
Cell Stem Cell . 2017 Dec; 21(6):725-729.e4. PMID: 29198942
Hematopoietic stem cells (HSCs) produce most cellular energy through glycolysis rather than through mitochondrial respiration. Consistent with this notion, mitochondrial mass has been reported to be low in HSCs. However,...
3.
Luchsinger L, Justino de Almeida M, Corrigan D, Mumau M, Snoeck H
Nature . 2016 Jan; 529(7587):528-31. PMID: 26789249
Haematopoietic stem cells (HSCs), which sustain production of all blood cell lineages, rely on glycolysis for ATP production, yet little attention has been paid to the role of mitochondria. Here...
4.
Gleason J, Corrigan D, Cox J, Reddi A, McGinnis L, Culotta V
PLoS One . 2011 Sep; 6(9):e24741. PMID: 21931840
Background: In diverse organisms, adaptation to low oxygen (hypoxia) is mediated through complex gene expression changes that can, in part, be mimicked by exposure to metals such as cobalt. Although...