Maria Jose Ortuno
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Explore the profile of Maria Jose Ortuno including associated specialties, affiliations and a list of published articles.
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11
Citations
277
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Recent Articles
1.
Chen B, Yu X, Horvath-Diano C, Ortuno M, Tschop M, Jastreboff A, et al.
Cell Metab
. 2024 Oct;
36(10):2173-2189.
PMID: 39357509
Readily available nutrient-rich foods exploit our inherent drive to overconsume, creating an environment of overnutrition. This transformative setting has led to persistent health issues, such as obesity and metabolic syndrome....
2.
Schneeberger M, Brice N, Pellegrino K, Parolari L, Shaked J, Page K, et al.
Nat Metab
. 2022 Dec;
5(1):183.
PMID: 36572826
No abstract available.
3.
Schneeberger M, Brice N, Pellegrino K, Parolari L, Shaked J, Page K, et al.
Nat Metab
. 2022 Nov;
4(11):1495-1513.
PMID: 36411386
Food intake and body weight are tightly regulated by neurons within specific brain regions, including the brainstem, where acute activation of dorsal raphe nucleus (DRN) glutamatergic neurons expressing the glutamate...
4.
Ortuno M, Schneeberger M, Ilanges A, Marchildon F, Pellegrino K, Friedman J, et al.
J Clin Invest
. 2021 Oct;
131(24).
PMID: 34673574
Contrasting with the predicted anorexigenic effect of increasing brain serotonin signaling, long-term use of selective serotonin reuptake inhibitor (SSRI) antidepressants correlates with body weight (BW) gain. This adverse outcome increases...
5.
Ortuno M, Ducy P
Expert Rev Endocrinol Metab
. 2019 Feb;
8(2):93-95.
PMID: 30736168
No abstract available.
6.
Ortuno M, Robinson S, Subramanyam P, Paone R, Huang Y, Guo X, et al.
Nat Med
. 2016 Sep;
22(10):1170-1179.
PMID: 27595322
The use of selective serotonin-reuptake inhibitors (SSRIs) has been associated with an increased risk of bone fracture, raising concerns about their increasingly broader usage. This deleterious effect is poorly understood,...
7.
Ortuno M, Susperregui A, Artigas N, Rosa J, Ventura F
Bone
. 2012 Nov;
52(2):548-56.
PMID: 23159876
Bone-specific transcription factors promote differentiation of mesenchymal precursors toward the osteoblastic cell phenotype. Among them, Runx2 and Osterix have been widely accepted as master osteogenic factors, since neither Runx2 nor...
8.
Rodriguez-Segui S, Ortuno M, Ventura F, Martinez E, Samitier J
J Mater Sci Mater Med
. 2012 Oct;
24(1):189-98.
PMID: 23080375
Cellular microarrays present a promising tool for multiplex evaluation of the signalling effect of substrate-immobilized factors on cellular differentiation. In this paper, we compare the early myoblast-to-osteoblast cell commitment steps...
9.
Susperregui A, Gamell C, Rodriguez-Carballo E, Ortuno M, Bartrons R, Rosa J, et al.
Mol Endocrinol
. 2011 Mar;
25(6):1006-17.
PMID: 21436263
Activation of p38 MAPK has been shown to be relevant for a number of bone morphogenetic protein (BMP) physiological effects. We report here the involvement of noncanonical phosphorylated mothers against...
10.
Ortuno M, Ruiz-Gaspa S, Rodriguez-Carballo E, Susperregui A, Bartrons R, Rosa J, et al.
J Biol Chem
. 2010 Aug;
285(42):31985-94.
PMID: 20682789
Osterix, a zinc finger transcription factor, is specifically expressed in osteoblasts and osteocytes of all developing bones. Because no bone formation occurs in Osx-null mice, Osterix is thought to be...