Maria Ferez
Overview
Explore the profile of Maria Ferez including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
185
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Recent Articles
1.
Knudson C, Ferez M, Alves-Peixoto P, Erkes D, Melo-Silva C, Tang L, et al.
J Virol
. 2021 Jul;
95(19):e0056621.
PMID: 34260270
Cytotoxic CD4 T lymphocytes (CD4-CTL) are important in antiviral immunity. For example, we have previously shown that in mice, CD4-CTL are important to control ectromelia virus (ECTV) infection. How viral...
2.
Melo-Silva C, Alves-Peixoto P, Heath N, Tang L, Montoya B, Knudson C, et al.
PLoS Pathog
. 2021 May;
17(5):e1009593.
PMID: 34015056
Type I interferons (IFN-I) are antiviral cytokines that signal through the ubiquitous IFN-I receptor (IFNAR). Following footpad infection with ectromelia virus (ECTV), a mouse-specific pathogen, C57BL/6 (B6) mice survive without...
3.
Ferez M, Knudson C, Lev A, Wong E, Alves-Peixoto P, Tang L, et al.
J Exp Med
. 2021 Mar;
218(5).
PMID: 33765134
Natural killer (NK) cell activation depends on the signaling balance of activating and inhibitory receptors. CD94 forms inhibitory receptors with NKG2A and activating receptors with NKG2E or NKG2C. We previously...
4.
Stotesbury C, Alves-Peixoto P, Montoya B, Ferez M, Nair S, Snyder C, et al.
J Immunol
. 2020 Feb;
204(6):1582-1591.
PMID: 32015010
NK cells play an important role in antiviral resistance. The integrin α2, which dimerizes with integrin β1, distinguishes NK cells from innate lymphoid cells 1 and other leukocytes. Despite its...
5.
Wong E, Montoya B, Ferez M, Stotesbury C, Sigal L
PLoS Pathog
. 2019 Dec;
15(12):e1008239.
PMID: 31877196
Cells sensing infection produce Type I interferons (IFN-I) to stimulate Interferon Stimulated Genes (ISGs) that confer resistance to viruses. During lympho-hematogenous spread of the mouse pathogen ectromelia virus (ECTV), the...
6.
Alves-Peixoto P, Ferez M, Knudson C, Melo-Silva C, Stotesbury C, Wong E, et al.
J Virol
. 2019 Dec;
94(5).
PMID: 31826990
It is well established that chronic viral infections can cause immune suppression, resulting in increased susceptibility to other infectious diseases. However, the effects of chronic viral infection on T-cell responses...
7.
Wong E, Montoya B, Stotesbury C, Ferez M, Xu R, Sigal L
Cell Rep
. 2019 Dec;
29(10):3047-3059.e3.
PMID: 31801072
During disseminating viral infections, a swift innate immune response (IIR) in the draining lymph node (dLN) that restricts systemic viral spread is critical for optimal resistance to disease. However, it...
8.
Alves-Peixoto P, Ferez M, Knudson C, Stotesbury C, Melo-Silva C, Wong E, et al.
J Virol
. 2019 Nov;
94(5).
PMID: 31776282
Chronic viral infections. like those of humans with cytomegalovirus, human immunodeficiency virus (even when under antiretroviral therapy), and hepatitis C virus or those of mice with lymphocytic choriomeningitis virus (LCMV)...
9.
Castro M, van Santen H, Ferez M, Alarcon B, Lythe G, Molina-Paris C
Front Immunol
. 2014 May;
5:132.
PMID: 24817867
T cell activation, initiated by T cell receptor (TCR) mediated recognition of pathogen-derived peptides presented by major histocompatibility complex class I or II molecules (pMHC), shows exquisite specificity and sensitivity,...
10.
Ferez M, Castro M, Alarcon B, van Santen H
J Immunol
. 2013 Dec;
192(1):52-8.
PMID: 24307729
Antigenic T cell stimulation requires interaction between the TCR of the T cell and cognate peptide-MHC molecules presented by the APC. Although studies with TCR-specific Abs and soluble peptide-MHC ligands...