Maria E Fuentes
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Explore the profile of Maria E Fuentes including associated specialties, affiliations and a list of published articles.
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16
Citations
456
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Recent Articles
1.
Montero-Cabrera L, Montero-Alejo A, Aspuru-Guzik A, Garcia de la Vega J, Piris M, Diaz-Fernandez L, et al.
J Chem Phys
. 2024 Jun;
160(21).
PMID: 38828812
CNDOL is an a priori, approximate Fockian for molecular wave functions. In this study, we employ several modes of singly excited configuration interaction (CIS) to model molecular excitation properties by...
2.
Kitchens W, Dong Y, Mathews D, Breeden C, Strobert E, Fuentes M, et al.
JCI Insight
. 2017 Mar;
2(5):e90317.
PMID: 28289708
The potential of costimulation blockade to serve as a novel transplant immunosuppression strategy has been explored for over 20 years, culminating in the recent clinical approval of belatacept for renal...
3.
Amatngalim G, Schrumpf J, Henic A, Dronkers E, Verhoosel R, Ordonez S, et al.
J Innate Immun
. 2017 Feb;
9(4):359-374.
PMID: 28171878
Antimicrobial proteins and peptides (AMPs) are a central component of the antibacterial activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung defense contributes to...
4.
Sidduri A, Budd D, Fuentes M, Lambros T, Ren Y, Roongta V, et al.
Bioorg Med Chem Lett
. 2014 Aug;
24(18):4450-4454.
PMID: 25155385
High throughput screening (HTS) of our chemical library identified 3-alkylamino-2-aryl-5H-imidazo[1,2,b]pyrazol-7-carbonitrile 1 as a potent antagonist of the LPA1 receptor (LPA1R). Further evaluation of this class of compounds indicated that LPA1R...
5.
Cheng D, Ma C, Niewoehner J, Dahl M, Tsai A, Zhang J, et al.
J Allergy Clin Immunol
. 2013 Jul;
132(2):455-62.
PMID: 23810153
Background: Thymic stromal lymphopoietin (TSLP) pathway blockade is a potential strategy for asthma treatment because the main activities of TSLP are activation of myeloid dendritic cells (mDCs) and modulation of...
6.
Tang X, Peng R, Phillips J, Deguzman J, Ren Y, Apparsundaram S, et al.
Am J Pathol
. 2013 Jun;
183(2):470-9.
PMID: 23759512
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of high unmet medical need. Although bromodomain (Brd) and extra terminal domain isoforms have recently been implicated in mediating inflammatory and...
7.
Tang X, Peng R, Ren Y, Apparsundaram S, Deguzman J, Bauer C, et al.
Mol Pharmacol
. 2012 Nov;
83(1):283-93.
PMID: 23115324
Epigenetic alterations, such as histone acetylation, regulate the signaling outcomes and phenotypic responses of fibroblasts after growth factor stimulation. The bromodomain and extra-terminal domain-containing proteins (Brd) bind to acetylated histone...
8.
Ren Y, Guo L, Tang X, Apparsundaram S, Kitson C, Deguzman J, et al.
Microvasc Res
. 2012 Oct;
85:59-67.
PMID: 23084965
Lysophosphatidic acid (LPA) is a class of bioactive lyso-phospholipid that mediates most of its biological effects through a family of G protein-coupled receptors of which six have been identified. The...
9.
Qian Y, Hamilton M, Sidduri A, Gabriel S, Ren Y, Peng R, et al.
J Med Chem
. 2012 Aug;
55(17):7920-39.
PMID: 22894757
Lysophosphatidic acid is a class of bioactive phospholipid that mediates most of its biological effects through LPA receptors, of which six isoforms have been identified. The recent results from LPA1...
10.
Rosales I, Orozco E, Bucio L, Fuentes M, Fuentes L
Acta Crystallogr Sect E Struct Rep Online
. 2011 May;
65(Pt 5):i33.
PMID: 21583725
A well crystallized powder sample of sodium holmium orthosilicate oxyapatite, Na(2.27)Ho(7.73)(SiO(4))(6)O(0.72), was obtained after mechanical milling and thermal treatment at 1123 K. Crystal structure analysis was performed from the results...