Maria C Marchetto
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Explore the profile of Maria C Marchetto including associated specialties, affiliations and a list of published articles.
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57
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2759
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Recent Articles
1.
Fernandes S, Revanna J, Pratt J, Hayes N, Marchetto M, Gage F
Front Neurosci
. 2024 Aug;
18:1434945.
PMID: 39156632
Age-related neurodegenerative diseases, like Alzheimer's disease (AD), are challenging diseases for those affected with no cure and limited treatment options. Functional, human derived brain tissues that represent the diverse genetic...
2.
Stern S, Zhang L, Wang M, Wright R, Rosh I, Hussein Y, et al.
Mol Psychiatry
. 2024 May;
29(10):3208-3222.
PMID: 38704507
Schizophrenia affects approximately 1% of the world population. Genetics, epigenetics, and environmental factors are known to play a role in this psychiatric disorder. While there is a high concordance in...
3.
Manole A, Wong T, Rhee A, Novak S, Chin S, Tsimring K, et al.
Cell Rep
. 2023 Dec;
42(12):113466.
PMID: 38039131
Biallelic mutations in the gene that encodes the enzyme N-glycanase 1 (NGLY1) cause a rare disease with multi-symptomatic features including developmental delay, intellectual disability, neuropathy, and seizures. NGLY1's activity in...
4.
Uzun Y, Santos R, Marchetto M, Padmanabhan K
bioRxiv
. 2023 Nov;
PMID: 37961249
Multi-electrode recording of neural activity in cultures offer opportunities for understanding how the structure of a network gives rise to function. Although it is hypothesized that network size is critical...
5.
Niemsiri V, Rosenthal S, Nievergelt C, Maihofer A, Marchetto M, Santos R, et al.
Mol Psychiatry
. 2023 Mar;
29(1):6-19.
PMID: 36991131
Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this...
6.
van den Hurk M, Lau S, Marchetto M, Mertens J, Stern S, Corti O, et al.
NPJ Parkinsons Dis
. 2022 Oct;
8(1):134.
PMID: 36258029
Complex genetic predispositions accelerate the chronic degeneration of midbrain substantia nigra neurons in Parkinson's disease (PD). Deciphering the human molecular makeup of PD pathophysiology can guide the discovery of therapeutics...
7.
Linker S, Narvaiza I, Hsu J, Wang M, Qiu F, Mendes A, et al.
Curr Biol
. 2022 Oct;
32(22):4797-4807.e5.
PMID: 36228612
Unique aspects of human behavior are often attributed to differences in the relative size and organization of the human brain: these structural aspects originate during early development. Recent studies indicate...
8.
Stern S, Lau S, Manole A, Rosh I, Mendel Percia M, Ben Ezer R, et al.
NPJ Parkinsons Dis
. 2022 Aug;
8(1):103.
PMID: 35948563
Several mutations that cause Parkinson's disease (PD) have been identified over the past decade. These account for 15-25% of PD cases; the rest of the cases are considered sporadic. Currently,...
9.
van Niekerk E, Kawaguchi R, Marques de Freria C, Groeniger K, Marchetto M, Dupraz S, et al.
Cell Rep Methods
. 2022 Jul;
2(7):100255.
PMID: 35880023
Neuronal cultures provide a basis for reductionist insights that rely on molecular and pharmacological manipulation. However, the inability to culture mature CNS neurons limits our understanding of adult neuronal physiology....
10.
Santos R, Mei A, Marchetto M
STAR Protoc
. 2022 Mar;
3(2):101261.
PMID: 35313707
Astrocytes are an essential component of the central nervous system for neuronal support and response to injury and disease. Here, we present a protocol to generate glial progenitor cells (GPCs)...