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Marcus A Breden

Explore the profile of Marcus A Breden including associated specialties, affiliations and a list of published articles. Areas
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Citations 333
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Recent Articles
1.
Zuo C, Baer J, Knolhoff B, Belle J, Liu X, de la Lastra A, et al.
J Exp Med . 2023 Mar; 220(6). PMID: 36951731
Tumor-associated macrophages (TAMs) are abundant in pancreatic ductal adenocarcinomas (PDACs). While TAMs are known to proliferate in cancer tissues, the impact of this on macrophage phenotype and disease progression is...
2.
Hegde S, Krisnawan V, Herzog B, Zuo C, Breden M, Knolhoff B, et al.
Cancer Cell . 2020 Mar; 37(3):289-307.e9. PMID: 32183949
Here, we utilized spontaneous models of pancreatic and lung cancer to examine how neoantigenicity shapes tumor immunity and progression. As expected, neoantigen expression during lung adenocarcinoma development leads to T ...
3.
Panni R, Herndon J, Zuo C, Hegde S, Hogg G, Knolhoff B, et al.
Sci Transl Med . 2019 Jul; 11(499). PMID: 31270275
Although checkpoint immunotherapies have revolutionized the treatment of cancer, not all tumor types have seen substantial benefit. Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in which very limited...