Chong Zuo
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Explore the profile of Chong Zuo including associated specialties, affiliations and a list of published articles.
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24
Citations
1093
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Recent Articles
1.
Baer J, Zuo C, Kang L, de la Lastra A, Borcherding N, Knolhoff B, et al.
Nat Immunol
. 2023 Aug;
24(9):1443-1457.
PMID: 37563309
Tissue-resident macrophages (TRMs) are long-lived cells that maintain locally and can be phenotypically distinct from monocyte-derived macrophages. Whether TRMs and monocyte-derived macrophages have district roles under differing pathologies is not...
2.
Michelson D, Zuo C, Verzi M, Benoist C, Mathis D
J Exp Med
. 2023 Jul;
220(10).
PMID: 37399024
Mimetic cells are medullary thymic epithelial cells (mTECs) that mimic extra-thymic cell types to tolerize T cells to self-antigens. Here, we dissected the biology of entero-hepato mTECs, mimetic cells expressing...
3.
Liu X, Hogg G, Zuo C, Borcherding N, Baer J, Lander V, et al.
Cancer Cell
. 2023 May;
41(6):1073-1090.e12.
PMID: 37236195
Chronic activation of inflammatory pathways and suppressed interferon are hallmarks of immunosuppressive tumors. Previous studies have shown that CD11b integrin agonists could enhance anti-tumor immunity through myeloid reprograming, but the...
4.
Zuo C, Baer J, Knolhoff B, Belle J, Liu X, de la Lastra A, et al.
J Exp Med
. 2023 Mar;
220(6).
PMID: 36951731
Tumor-associated macrophages (TAMs) are abundant in pancreatic ductal adenocarcinomas (PDACs). While TAMs are known to proliferate in cancer tissues, the impact of this on macrophage phenotype and disease progression is...
5.
Peng H, Li L, Zuo C, Chen M, Zhang X, Myers N, et al.
Front Immunol
. 2022 Dec;
13:1039226.
PMID: 36569934
Background: Cancer neoantigens are important targets of cancer immunotherapy and neoantigen vaccines are currently in development in pancreatic ductal adenocarcinoma (PDAC) and other cancer types. Immune regulatory mechanisms in pancreatic...
6.
Zheng Q, Wang T, Mao J, Chu G, Liang L, Jing Y, et al.
Nat Protoc
. 2022 Nov;
18(2):530-554.
PMID: 36323865
Ubiquitination regulates almost every life process of eukaryotes. The study of the ubiquitin (Ub) coupling or decoupling process and the interaction study of Ub-Ub binding protein have always been the...
7.
Lander V, Belle J, Kingston N, Herndon J, Hogg G, Liu X, et al.
Cancer Discov
. 2022 Sep;
12(12):2774-2799.
PMID: 36165893
Significance: Checkpoint immunotherapeutics have not been effective in PDAC, even when combined with RT. One possible explanation is that RT fails to prime T-cell responses in PDAC. Here, we show...
8.
Zhou D, Jayasinghe R, Chen S, Herndon J, Iglesia M, Navale P, et al.
Nat Genet
. 2022 Aug;
54(9):1390-1405.
PMID: 35995947
Pancreatic ductal adenocarcinoma is a lethal disease with limited treatment options and poor survival. We studied 83 spatial samples from 31 patients (11 treatment-naïve and 20 treated) using single-cell/nucleus RNA...
9.
Zuo C, Ding R, Wu X, Wang Y, Chu G, Liang L, et al.
Angew Chem Int Ed Engl
. 2022 May;
61(28):e202201887.
PMID: 35514243
Sortase A (SrtA)-mediated ligation, a popular method for protein labeling and semi-synthesis, is limited by its reversibility and dependence on the LPxTG motif, where "x" is any amino acid. Here,...
10.
Pan M, Zheng Q, Wang T, Liang L, Mao J, Zuo C, et al.
Nature
. 2021 Nov;
600(7888):334-338.
PMID: 34789879
The N-degron pathway targets proteins that bear a destabilizing residue at the N terminus for proteasome-dependent degradation. In yeast, Ubr1-a single-subunit E3 ligase-is responsible for the Arg/N-degron pathway. How Ubr1...