Marcel Bruinenberg
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Explore the profile of Marcel Bruinenberg including associated specialties, affiliations and a list of published articles.
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7021
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Recent Articles
1.
Wang Z, Emmerich A, Pillon N, Moore T, Hemerich D, Cornelis M, et al.
Nat Genet
. 2022 Sep;
54(9):1332-1344.
PMID: 36071172
Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in...
2.
Amini M, Vonk J, Abbasi A, Prins B, Bruinenberg M, Franke L, et al.
Twin Res Hum Genet
. 2018 Mar;
21(2):89-100.
PMID: 29506594
Blood eosinophil count is associated with a variety of common complex outcomes in epidemiological observation. The aim of this study was to explore the causal association between determined blood eosinophil...
3.
Justice A, Winkler T, Feitosa M, Graff M, Fisher V, Young K, et al.
Nat Commun
. 2017 Apr;
8:14977.
PMID: 28443625
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data...
4.
Nolte I, van der Most P, Alizadeh B, de Bakker P, Boezen H, Bruinenberg M, et al.
Eur J Hum Genet
. 2017 Apr;
25(7):877-885.
PMID: 28401901
Despite the recent explosive rise in number of genetic markers for complex disease traits identified in genome-wide association studies, there is still a large gap between the known heritability of...
5.
Amini M, Bashirova D, Prins B, Corpeleijn E, Bruinenberg M, Franke L, et al.
PLoS One
. 2016 Dec;
11(12):e0168480.
PMID: 27978545
There is ongoing debate on the association between eosinophil count and diseases, as previous studies were inconsistent. We studied the relationship of eosinophil count with 22 complex metabolic, cardiac, and...
6.
Ried J, Jeff M J, Chu A, Bragg-Gresham J, Dongen J, Huffman J, et al.
Nat Commun
. 2016 Nov;
7:13357.
PMID: 27876822
Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that...
7.
Winkler T, Justice A, Graff M, Barata L, Feitosa M, Chu S, et al.
PLoS Genet
. 2016 Jun;
12(6):e1006166.
PMID: 27355579
[This corrects the article DOI: 10.1371/journal.pgen.1005378.].
8.
Winkler T, Justice A, Graff M, Barata L, Feitosa M, Chu S, et al.
PLoS Genet
. 2015 Oct;
11(10):e1005378.
PMID: 26426971
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body...
9.
Locke A, Kahali B, Berndt S, Justice A, Pers T, Day F, et al.
Nature
. 2015 Feb;
518(7538):197-206.
PMID: 25673413
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index...
10.
Shungin D, Winkler T, Croteau-Chonka D, Ferreira T, Locke A, Magi R, et al.
Nature
. 2015 Feb;
518(7538):187-196.
PMID: 25673412
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat...