Daniel I Chasman
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Explore the profile of Daniel I Chasman including associated specialties, affiliations and a list of published articles.
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391
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44434
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Recent Articles
1.
Sonawalla A, Chasman D, Chan Y
J Clin Endocrinol Metab
. 2025 Mar;
PMID: 40059721
Background: In women, both earlier and later age at menarche (AAM) are associated with increased risk of coronary artery disease (CAD). This study examined if the relationship of AAM with...
2.
Choi S, Jurgens S, Xiao L, Hill M, Haggerty C, Sveinbjornsson G, et al.
Nat Genet
. 2025 Mar;
57(3):548-562.
PMID: 40050430
Atrial fibrillation (AF) is a prevalent and morbid abnormality of the heart rhythm with a strong genetic component. Here, we meta-analyzed genome and exome sequencing data from 36 studies that...
3.
Roselli C, Surakka I, S Olesen M, Sveinbjornsson G, Marston N, Choi S, et al.
Nat Genet
. 2025 Mar;
57(3):539-547.
PMID: 40050429
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-analysis of genome-wide association studies increased the power...
4.
Westerman K, Patel C, Meigs J, Chasman D, Manning A
Genes Nutr
. 2025 Mar;
20(1):3.
PMID: 40038624
Discovery and translation of gene-environment interactions (GxEs) influencing clinical outcomes is limited by low statistical power and poor mechanistic understanding. Molecular omics data may help address these limitations, but their...
5.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
6.
Marston N, Kamanu F, Melloni G, Schnitzler G, Hakim A, Ma R, et al.
Nat Med
. 2025 Feb;
PMID: 40011692
The role of endothelial cell (EC) dysfunction in contributing to an individual's susceptibility to coronary atherosclerosis and how low-density lipoprotein cholesterol (LDL-C) concentrations might modify this relationship have not been...
7.
Magavern E, Deshmukh H, Asselin G, Theusch E, Trompet S, Li X, et al.
Pharmacol Res
. 2025 Jan;
212:107575.
PMID: 39798939
Statins are first-line treatments in the primary and secondary prevention of cardiovascular disease. Clinical studies show statins act independently of lipid-lowering mechanisms to decrease C-reactive protein (CRP), an inflammation marker....
8.
Westerman K, Kilpelainen T, Sevilla-Gonzalez M, Connelly M, Wood A, Tsai M, et al.
Genet Epidemiol
. 2025 Jan;
49(1):e22607.
PMID: 39764704
Large-scale gene-environment interaction (GxE) discovery efforts often involve analytical compromises for the sake of data harmonization and statistical power. Refinement of exposures, covariates, outcomes, and population subsets may be helpful...
9.
Sonawalla A, Chasman D, Chan Y
medRxiv
. 2025 Jan;
PMID: 39763517
Background: In women, both earlier and later age at menarche (AAM) are associated with increased risk of coronary artery disease (CAD). This study sought to determine if the relationship of...
10.
Chasman D, Guo Y, Chan A, Rist P, Staller K
Neurol Genet
. 2024 Dec;
10(6):e200201.
PMID: 39677849
Background And Objectives: Migraine is strongly comorbid with irritable bowel syndrome (IBS), one of several gastrointestinal (GI) conditions that are distinguished by symptomatic profiles that are partly overlapping. Potential shared...