Marc Pilon
Overview
Explore the profile of Marc Pilon including associated specialties, affiliations and a list of published articles.
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59
Citations
1061
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Recent Articles
1.
Ruiz M, Devkota R, Bergh P, Nik A, Blid Skoldheden S, Mondejar-Duran J, et al.
FASEB J
. 2024 Jul;
38(14):e23815.
PMID: 38989587
To investigate how the fatty acid composition of brain phospholipids influences brain-specific processes, we leveraged the AdipoR2 (adiponectin receptor 2) knockout mouse model in which the brain is enlarged, and...
2.
Zhang J, Ruiz M, Bergh P, Henricsson M, Stojanovic N, Devkota R, et al.
Nat Commun
. 2024 Mar;
15(1):2315.
PMID: 38485951
The cellular membrane in male meiotic germ cells contains a unique class of phospholipids and sphingolipids that is required for male reproduction. Here, we show that a conserved membrane fluidity...
3.
Pilon M, Ruiz M
Bioessays
. 2023 Jun;
45(9):e2300079.
PMID: 37345585
Recently published work showed that members of the PAQR protein family are activated by cell membrane rigidity and contribute to our ability to eat a wide variety of diets. Cell...
4.
Ruiz M, Devkota R, Kaper D, Ruhanen H, Busayavalasa K, Radovic U, et al.
J Biol Chem
. 2023 May;
299(6):104799.
PMID: 37164154
The human AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 are multipass plasma membrane proteins that protect cells against membrane rigidification. However, how AdipoR2 promotes membrane fluidity mechanistically is not clear....
5.
Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, et al.
Cardiovasc Res
. 2023 Mar;
119(7):1537-1552.
PMID: 36880401
Aims: Pro-protein convertase subtilisin-kexin type 9 (PCSK9), which is expressed mainly in the liver and at low levels in the heart, regulates cholesterol levels by directing low-density lipoprotein receptors to...
6.
Ruiz M, Panagaki D, Hoog J, Pilon M
J Lipid Res
. 2023 Jan;
64(3):100335.
PMID: 36682703
No abstract available.
7.
Palmgren H, Petkevicius K, Bartesaghi S, Ahnmark A, Ruiz M, Nilsson R, et al.
Diabetes
. 2022 Dec;
72(10):1350-1363.
PMID: 36580483
Increased saturated fatty acid (SFA) levels in membrane phospholipids have been implicated in the development of metabolic disease. Here, we tested the hypothesis that increased SFA content in cell membranes...
8.
Ruiz M, Devkota R, Panagaki D, Bergh P, Kaper D, Henricsson M, et al.
Nat Commun
. 2022 Nov;
13(1):7162.
PMID: 36418331
Cells and organisms require proper membrane composition to function and develop. Phospholipids are the major component of membranes and are primarily acquired through the diet. Given great variability in diet...
9.
Petkevicius K, Palmgren H, Glover M, Ahnmark A, Andreasson A, Madeyski-Bengtson K, et al.
Nat Commun
. 2022 Oct;
13(1):6020.
PMID: 36241646
The fatty acid composition of phosphatidylethanolamine (PE) determines cellular metabolism, oxidative stress, and inflammation. However, our understanding of how cells regulate PE composition is limited. Here, we identify a genetic...
10.
Ruiz M, Svensk E, Einarsson E, Grahn E, Pilon M
Biochim Biophys Acta Biomembr
. 2022 May;
1864(9):183959.
PMID: 35588889
Defects in cell membrane homeostasis are implicated in numerous disorders, including cancer, neurodegeneration and diabetes. There is therefore a need for a powerful model to study membrane homeostasis and to...