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Marc M Mareel

Explore the profile of Marc M Mareel including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 83
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Recent Articles
1.
Bracke M, Roman B, Stevens C, Mus L, Parmar V, de Wever O, et al.
J Vis Exp . 2015 Jul; (100):e52792. PMID: 26131648
The goal of the chick heart assay is to offer a relevant organ culture method to study tumor invasion in three dimensions. The assay can distinguish between invasive and non-invasive...
2.
Bracke M, Parmar V, DePass A, Stevens C, Vanhoecke B, Mareel M
Methods Mol Biol . 2013 Oct; 1070:93-106. PMID: 24092434
Tumors are microecosystems in which a continuous cross talk between cancer cells and host cells decides on the invasive behavior of the tumor cell population as a whole (Mareel et...
3.
Debruyne D, Mareel M, Bracke M
Eur J Cancer Prev . 2010 Apr; 19(3):227-38. PMID: 20361424
Earlier observations suggested that opioids modify cell-substrate adhesion on agar. In this study, we wanted to investigate whether opioids also interfere with cell adhesion to biologically relevant substrates, including interstitial...
4.
Debruyne P, Vermeulen S, Berx G, Pocard M, Correia da Rocha A, Li X, et al.
Oncogene . 2003 Oct; 22(46):7199-208. PMID: 14562048
In subclones of the human colon cancer LoVo cell line, there is a reproducible spontaneous transition from an epithelioid (E) to a round (R) morphotype. The E to R transition...
5.
Suriano G, Mulholland D, de Wever O, Ferreira P, Mateus A, Bruyneel E, et al.
Oncogene . 2003 Aug; 22(36):5716-9. PMID: 12944922
E-cadherin germline missense mutations have been shown to be responsible for significant loss of protein activity. A new cytoplasmic E-cadherin germline missense mutation (V832 M) was recently identified in a...
6.
Leroy A, de Bruyne G, Oomen L, Mareel M
Anticancer Res . 2003 Apr; 23(1A):27-32. PMID: 12680191
Alkylphospholipids, such as the antitumor ether lipid 1-O-octadecyl-2-O-methylglycero-3-phosphocholine, modulate cancer cell invasion through changes in the adherens junction E-cadherin complex, a major organizer of epithelia. We wanted to know whether...
7.
Parmar V, Sharma N, Husain M, Watterson A, Kumar J, Samuelson L, et al.
Bioorg Med Chem . 2003 Mar; 11(6):913-29. PMID: 12614877
Invasion is the hallmark of malignant tumors, and is responsible for the bad prognosis of the untreated cancer patients. The search for anti-invasive treatments led us to screen compounds of...
8.
van Aken E, de Wever O, Van Hoorde L, Bruyneel E, De Laey J, Mareel M
Invest Ophthalmol Vis Sci . 2003 Jan; 44(2):463-72. PMID: 12556370
Purpose: To investigate the role of N-cadherin and hepatocyte growth factor (HGF) in the invasion of collagen type I by human retinal pigment epithelial (RPE) cells. Methods: RPE sheets from...
9.
Maubach J, Bracke M, Heyerick A, Depypere H, Serreyn R, Mareel M, et al.
J Chromatogr B Analyt Technol Biomed Life Sci . 2002 Dec; 784(1):137-44. PMID: 12504192
A new and reliable HPLC method for the quantitation of daidzein, equol, and genistein in human breast tissue has been developed. The method was applied to biopsies from women undergoing...
10.
Brack M, Boterberg T, Depypere H, Stove C, Leclercq G, Mareel M
Adv Exp Med Biol . 2002 Jun; 505:135-9. PMID: 12083457
Two effects of the citrus methoxyflavone tangeretin on cell-cell interactions are biologically relevant. Firstly, tangeretin upregulates the function of the E-cadherin/catenin complex in human MCF-7/6 breast carcinoma cells. This leads...