Marc-Henri Stern
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Explore the profile of Marc-Henri Stern including associated specialties, affiliations and a list of published articles.
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135
Citations
5278
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Recent Articles
11.
Villy M, Le Ven A, Le Mentec M, Masliah-Planchon J, Houy A, Bieche I, et al.
J Natl Cancer Inst
. 2023 Dec;
116(4):580-587.
PMID: 38060262
Background: Monoallelic germline MBD4 pathogenic variants were recently reported to cause a predisposition to uveal melanoma, associated with a specific tumor mutational signature and good response to immunotherapy. Monoallelic tumor...
12.
Callens C, Rodrigues M, Briaux A, Frouin E, Eeckhoutte A, Pujade-Lauraine E, et al.
Oncogene
. 2023 Nov;
42(48):3556-3563.
PMID: 37945748
The bevacizumab (bev)/olaparib (ola) maintenance regimen was approved for BRCA1/2-mutated (BRCAmut) and Homologous Recombination Deficient (HRD) high-grade Advanced Ovarian Cancer (AOC) first line setting, based on a significantly improved progression-free...
13.
Schwartz M, Ibadioune S, Chansavang A, Vacher S, Caputo S, Delhomelle H, et al.
J Med Genet
. 2023 Sep;
61(3):284-288.
PMID: 37748860
Purpose: Mosaic promoter methylation (meth) increases the risk of early-onset breast cancer, triple-negative breast cancer and ovarian cancer. As mosaic meth are believed to occur de novo, their role in...
14.
Gentien D, Saberi-Ansari E, Servant N, Jolly A, De La Grange P, Nemati F, et al.
Cell Rep
. 2023 Sep;
42(9):113132.
PMID: 37708024
Uveal melanoma (UM) is a rare cancer resulting from the transformation of melanocytes in the uveal tract. Integrative analysis has identified four molecular and clinical subsets of UM. To improve...
15.
Bland P, Saville H, Wai P, Curnow L, Muirhead G, Nieminuszczy J, et al.
Nat Genet
. 2023 Jul;
55(8):1311-1323.
PMID: 37524790
SF3B1 hotspot mutations are associated with a poor prognosis in several tumor types and lead to global disruption of canonical splicing. Through synthetic lethal drug screens, we identify that SF3B1...
16.
Mariani P, Torossian N, Van Laere S, Vermeulen P, De Koning L, Roman-Roman S, et al.
Br J Cancer
. 2023 Jul;
129(5):772-781.
PMID: 37443346
Background: The immune landscape of uveal melanoma liver metastases (UMLM) has not been sufficiently studied. Methods: Immune cell infiltrates (ICIs), PD-1 and PD-L1 were characterised in 62 UMLM and 28...
17.
Ma S, Huis Int Veld R, Houy A, Stern M, Rich C, Ossendorp F, et al.
Invest Ophthalmol Vis Sci
. 2023 Jun;
64(7):10.
PMID: 37272766
Purpose: The virus-like drug conjugate belzupacap sarotalocan (AU-011), currently under clinical investigation for first-line treatment of primary uveal melanoma (UM), shows enhanced tumor specificity by targeting heparan sulfate proteoglycans (HSPG)....
18.
Champiat S, Salaun H, Lucibello F, Scoazec J, Besse B, Lalanne A, et al.
JCO Precis Oncol
. 2023 May;
7:e2200363.
PMID: 37224427
No abstract available.
19.
Tarin M, Nemati F, Decaudin D, Canbezdi C, Marande B, Silva L, et al.
Cancers (Basel)
. 2023 May;
15(8).
PMID: 37190207
Uveal Melanoma (UM) is a rare and malignant intraocular tumor with dismal prognosis. Even if radiation or surgery permit an efficient control of the primary tumor, up to 50% of...
20.
Ter Brugge P, Moser S, Bieche I, Kristel P, Ibadioune S, Eeckhoutte A, et al.
Nat Commun
. 2023 Apr;
14(1):1958.
PMID: 37029129
The high frequency of homologous recombination deficiency (HRD) is the main rationale of testing platinum-based chemotherapy in triple-negative breast cancer (TNBC), however, the existing methods to identify HRD are controversial...