Manuel Valenzuela-Valderrama
Overview
Explore the profile of Manuel Valenzuela-Valderrama including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
152
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Recent Articles
1.
Faundes-Gandolfo N, Jara-Gutierrez C, Parraga M, Montenegro I, Vera W, Escobar M, et al.
BMC Complement Med Ther
. 2024 Jul;
24(1):269.
PMID: 39010075
Background: The leaves of Kalanchoe pinnata (Lam.) Pers. (K. pinnata), a succulent plant native to tropical regions, are used as a medicinal alternative against cancer in several countries worldwide; however,...
2.
Palacios E, Lobos-Gonzalez L, Guerrero S, Kogan M, Shao B, Heinecke J, et al.
J Neuroinflammation
. 2023 Mar;
20(1):66.
PMID: 36895046
Background: Helicobacter pylori (Hp) infects the stomach of 50% of the world's population. Importantly, chronic infection by this bacterium correlates with the appearance of several extra-gastric pathologies, including neurodegenerative diseases....
3.
Carrasco N, Garrido M, Montenegro I, Madrid A, Hartley R, Gonzalez I, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674960
is a native South American plant used ancestrally by Mapuche people to treat gastrointestinal ailments. flower extracts are rich in molecules with therapeutic potential, including the sesquiterpene lactone leptocarpin, which...
4.
Gonzalez M, Burgos-Ravanal R, Shao B, Heinecke J, Valenzuela-Valderrama M, Corvalan A, et al.
Front Oncol
. 2022 Oct;
12:962920.
PMID: 36313672
Chronic () infection is considered the main risk factor for the development of gastric cancer. Pathophysiological changes in the gastric mucosa initiated by this bacterium can persist even after pharmacological...
5.
Rojo D, Madrid A, San Martin S, Parraga M, Pinhal M, Villena J, et al.
Molecules
. 2022 May;
27(10).
PMID: 35630523
The cancer-preventive agent Resveratrol (RSV) [3,5,4'-trihydroxytrans-stilbene] is a widely recognized antioxidant molecule with antitumoral potential against several types of cancers, including prostate, hepatic, breast, skin, colorectal, and pancreatic. Herein, we...
6.
Garrido M, Fredes A, Lobos-Gonzalez L, Valenzuela-Valderrama M, Vera D, Romero C
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052757
Epithelial ovarian cancer (EOC) is one of the deadliest gynaecological malignancies. The late diagnosis is frequent due to the absence of specific symptomatology and the molecular complexity of the disease,...
7.
Garrido M, Torres I, Avila A, Chnaiderman J, Valenzuela-Valderrama M, Aramburo J, et al.
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33081171
Nerve Growth Factor (NGF) and its high-affinity receptor tropomyosin receptor kinase A (TRKA) increase their expression during the progression of epithelial ovarian cancer (EOC), promoting cell proliferation and angiogenesis through...
8.
Garrido M, Salvatierra R, Valenzuela-Valderrama M, Vallejos C, Bruneau N, Hernandez A, et al.
Pharmaceuticals (Basel)
. 2020 Oct;
13(10).
PMID: 33081077
Epithelial ovarian cancer (EOC) is a lethal gynaecological neoplasm characterized by rapid growth and angiogenesis. Nerve growth factor (NGF) and its high affinity receptor tropomyosin receptor kinase A (TRKA) contribute...
9.
Sanhueza C, Bennett J, Valenzuela-Valderrama M, Contreras P, Lobos-Gonzalez L, Campos A, et al.
Cancers (Basel)
. 2020 Aug;
12(9).
PMID: 32825247
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently...
10.
Valenzuela-Valderrama M, Carrasco-Veliz N, Gonzalez I, Dreyse P, Palavecino C
Photodiagnosis Photodyn Ther
. 2020 Jun;
31:101882.
PMID: 32565179
Background: Carbapenemase-producing strains of Klebsiella pneumoniae (KPC) are one of the multi-drug resistant bacteria with the highest risk for human health. The colistin is the only antibiotic option against KPC;...