Pamela Contreras
Overview
Explore the profile of Pamela Contreras including associated specialties, affiliations and a list of published articles.
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13
Citations
107
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0
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Recent Articles
1.
Guncay T, Concha J, Lobos P, More J, Bruna B, Sansores D, et al.
J Gerontol A Biol Sci Med Sci
. 2025 Jan;
PMID: 39823270
Postoperative delirium (POD), an acute cognitive dysfunction linked to morbidity and mortality, is characterized by memory impairments and disturbances in consciousness, particularly in patients aged 65 and older. Neuroinflammation and...
2.
Simon L, Torres K, Contreras P, Diaz-Valdivia N, Leyton L, Quest A
Biomed Pharmacother
. 2024 Jun;
176:116841.
PMID: 38834004
Metastasis is the leading cause of cancer-related deaths, making the development of novel, more effective therapies imperative to alleviate patient suffering. Metabolic switching is a hallmark of cancer cells that...
3.
Wannan C, Nelson B, Addington J, Allott K, Anticevic A, Arango C, et al.
Schizophr Bull
. 2024 Mar;
50(3):496-512.
PMID: 38451304
This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict...
4.
Pena-Oyarzun D, Flores T, Torres V, Quest A, Lobos-Gonzalez L, Kretschmar C, et al.
Clin Cancer Res
. 2023 Oct;
30(1):209-223.
PMID: 37812478
Purpose: Oral squamous cell carcinoma (OSCC) is commonly preceded by potentially malignant lesions, referred to as oral dysplasia. We recently reported that oral dysplasia is associated with aberrant activation of...
5.
Perez-Nunez R, Chamorro A, Gonzalez M, Contreras P, Artigas R, Corvalan A, et al.
J Neuroinflammation
. 2023 Jan;
20(1):5.
PMID: 36609298
Background: In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis...
6.
Perez L, Leon J, Lopez J, Rojas D, Reyes M, Contreras P, et al.
Int J Mol Sci
. 2022 Oct;
23(20).
PMID: 36293394
Wound healing is a highly regulated multi-step process that involves a plethora of signals. Blood perfusion is crucial in wound healing and abnormalities in the formation of new blood vessels...
7.
Diaz-Valdivia N, Simon L, Diaz J, Martinez-Meza S, Contreras P, Burgos-Ravanal R, et al.
Cancers (Basel)
. 2022 Jun;
14(12).
PMID: 35740528
Cancer cells often display impaired mitochondrial function, reduced oxidative phosphorylation, and augmented aerobic glycolysis (Warburg effect) to fulfill their bioenergetic and biosynthetic needs. Caveolin-1 (CAV1) is a scaffolding protein that...
8.
Garland M, Lukac D, Contreras P
J Cancer Educ
. 2022 Apr;
38(2):664-668.
PMID: 35445292
The Internet is a major source of patient information on medical subjects. Several studies have evaluated the content of English medical material for patient use. However, few have focused on...
9.
Brenet M, Martinez S, Perez-Nunez R, Perez L, Contreras P, Diaz J, et al.
Front Cell Dev Biol
. 2021 Jan;
8:592442.
PMID: 33511115
Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma...
10.
Sanhueza C, Bennett J, Valenzuela-Valderrama M, Contreras P, Lobos-Gonzalez L, Campos A, et al.
Cancers (Basel)
. 2020 Aug;
12(9).
PMID: 32825247
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently...