Manika Pal-Bhadra
Overview
Explore the profile of Manika Pal-Bhadra including associated specialties, affiliations and a list of published articles.
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53
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1050
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Recent Articles
1.
Bagul C, Rao G, Veena I, Kulkarni R, Tamboli J, Akunuri R, et al.
Mol Divers
. 2022 Sep;
27(3):1185-1202.
PMID: 36114912
A library of benzimidazole briged pyrazolo[1,5-a]pyrimidine (6a-q) was designed, synthesized and subjected for evaluation for cytotoxic potential. Antiproliferative activity, ranging from 3.1-51.5 μM, was observed against a panel of cancer...
2.
Goud N, Makani V, Pranay J, Alvala R, Qureshi I, Kumar P, et al.
Bioorg Chem
. 2020 Feb;
97:103663.
PMID: 32106038
In present study, a new series of 4, 7-disubstituted coumarin derivatives (7a-y) have been synthesized as galectin-1 targeting apoptosis inducing agents and evaluated for their in vitro cytotoxic potentials against...
3.
Khan I, Garikapati K, Setti A, Shaik A, Makani V, Shareef M, et al.
Eur J Med Chem
. 2018 Dec;
163:636-648.
PMID: 30562699
In an attempt to develop potent and selective anticancer agents, a series of 15 conjugates of 1,4-dihydroindeno[1,2-c]pyrazole chalcone (12a-o) were designed, synthesized and evaluated for their antiproliferative activity against MCF7,...
4.
Bagul C, Rao G, Makani V, Tamboli J, Pal-Bhadra M, Kamal A
Medchemcomm
. 2018 Aug;
8(9):1810-1816.
PMID: 30108891
A series of pyrazolo[1,5-]pyrimidines substituted at C5 with 1-phenylprop-2-en-1-one () and 3-phenylprop-2-en-1-one () was synthesized and evaluated for antiproliferative activity. Among them, was found to be the most active compound...
5.
Khan I, Garikapati K, Shaik A, Makani V, Rahim A, Shareef M, et al.
Eur J Med Chem
. 2017 Dec;
144:104-115.
PMID: 29268127
A series of 1, 4-dihydroindeno-[1,2-c] pyrazole linked oxindole conjugates have been synthesized by using Knoevenagel condensation method and further evaluated for their antiproliferative activity against HeLa, A549 and MDA-MB-231 human...
6.
Mekala J, Naushad S, Ponnusamy L, Arivazhagan G, Sakthiprasad V, Pal-Bhadra M
Gene
. 2017 Oct;
641:248-258.
PMID: 29038000
MicroRNAs (miRNAs) are a class of small, non-coding RNAs that are involved in the regulation of gene expression at the post-transcriptional level. MicroRNAs play an important role in cancer cell...
7.
Shaik A, Rao G, Kumar G, Patel N, Reddy V, Khan I, et al.
Eur J Med Chem
. 2017 Aug;
139:305-324.
PMID: 28803046
Cancer has been established as the "Emperor of all maladies". In recent years, medicinal chemistry has focused on identifying novel anti-cancer compounds; though discovery of these compounds appears to be...
8.
Bhadra U, Patra P, Pal-Bhadra M
Mol Neurobiol
. 2017 May;
55(4):3564-3576.
PMID: 28516429
Circadian rhythm which governs basic physiological activities like sleeping, feeding and energy consumption is regulated by light-controlled central clock genes in the pacemaker neuron. The timekeeping machinery with unique transcriptional...
9.
Bhadra U, Patra P, Chhatai J, Pal-Bhadra M
Mol Med
. 2016 Oct;
22:759-775.
PMID: 27704139
MicroRNAs (miRNAs) are well preserved in every animal. These pigmy sized non-coding RNAs (21-23 nt), scattered in genome, are responsible for micromanaging the versatile gene regulations. Involvement of miRNAs was...
10.
Bhadra U, Gandhi S, Palaparthi R, Balyan M, Pal-Bhadra M
FEBS J
. 2016 Jul;
283(18):3457-70.
PMID: 27456781
Unlabelled: The loss of the entire X chromosome in Drosophila males generates a genome-wide aneuploid effect. We have employed a systems biology approach (microarray) to investigate the global aneuploid effect...