Manfred Wiessler
Overview
Explore the profile of Manfred Wiessler including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
990
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Recent Articles
1.
Kipper K, Lundius E, Curic V, Nikic I, Wiessler M, Lemke E, et al.
ACS Synth Biol
. 2016 Oct;
6(2):233-255.
PMID: 27775882
Small synthetic fluorophores are in many ways superior to fluorescent proteins as labels for imaging. A major challenge is to use them for a protein-specific labeling in living cells. Here,...
2.
Pagel M, Meier R, Braun K, Wiessler M, Beck-Sickinger A
Org Biomol Chem
. 2016 Apr;
14(21):4809-16.
PMID: 27117044
Solid phase peptide synthesis (SPPS) is the method of choice to produce peptides. Several protecting groups enable specific modifications. However, complex peptide conjugates usually require a rather demanding conjugation strategy,...
3.
Pagel M, Hassert R, John T, Braun K, Wiessler M, Abel B, et al.
Angew Chem Int Ed Engl
. 2016 Mar;
55(15):4826-30.
PMID: 26938787
Promotion of cell adhesion on biomaterials is crucial for the long-term success of a titanium implant. Herein a novel concept is highlighted combining very stable and affine titanium surface adhesive...
4.
Komljenovic D, Wiessler M, Waldeck W, Ehemann V, Pipkorn R, Schrenk H, et al.
Theranostics
. 2016 Jan;
6(1):131-41.
PMID: 26722379
Personalized anti-cancer medicine is boosted by the recent development of molecular diagnostics and molecularly targeted drugs requiring rapid and efficient ligation routes. Here, we present a novel approach to synthetize...
5.
Pipkorn R, Braun K, Wiessler M, Waldeck W, Schrenk H, Koch M, et al.
Int J Med Sci
. 2014 May;
11(7):697-706.
PMID: 24843319
Advances in imaging diagnostics using magnetic resonance tomography (MRT), positron emission tomography (PET) and fluorescence imaging including near infrared (NIR) imaging methods are facilitated by constant improvement of the concepts...
6.
Waldeck W, Mueller G, Glatting K, Hotz-Wagenblatt A, Diessl N, Chotewutmonti S, et al.
Int J Med Sci
. 2013 Jul;
10(9):1136-48.
PMID: 23869190
The highly organized DNA architecture inside of the nuclei of cells is accepted in the scientific world. In the human genome about 3 billion nucleotides are organized as chromatin in...
7.
Pipkorn R, Rawer S, Wiessler M, Waldeck W, Koch M, Schrenk H, et al.
Int J Med Sci
. 2013 Feb;
10(3):331-7.
PMID: 23423830
The personalized medicine, also documented as "individualized medicine", is an effective and therapeutic approach. It is designed to treat the disease of the individual patient whose precise differential gene expression...
8.
Marano G, Gronewold C, Frank M, Merling A, Kliem C, Sauer S, et al.
Beilstein J Org Chem
. 2012 Sep;
8:787-803.
PMID: 23015827
Oligosaccharides aberrantly expressed on tumor cells influence processes such as cell adhesion and modulation of the cell's microenvironment resulting in an increased malignancy. Schmidt's imidate strategy offers an effective method...
9.
Hassert R, Pagel M, Ming Z, Haupl T, Abel B, Braun K, et al.
Bioconjug Chem
. 2012 Sep;
23(10):2129-37.
PMID: 22989005
Multifunctionality is gaining more and more importance in the field of improved biomaterials. Especially peptides feature a broad chemical variability and are versatile mediators between inorganic surfaces and living cells....
10.
Borrmann A, Milles S, Plass T, Dommerholt J, Verkade J, Wiessler M, et al.
Chembiochem
. 2012 Sep;
13(14):2094-9.
PMID: 22945333
Visualizing biomolecules by fluorescent tagging is a powerful method for studying their behaviour and function inside cells. We prepared and genetically encoded an unnatural amino acid (UAA) that features a...