Manfred Wiessler
Overview
Explore the profile of Manfred Wiessler including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
990
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0
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Recent Articles
11.
Braun K, Beining M, Wiessler M, Lammers T, Pipkorn R, Hennrich U, et al.
Int J Med Sci
. 2012 Jul;
9(5):339-52.
PMID: 22811608
With the increase in molecular diagnostics and patient-specific therapeutic approaches, the delivery and targeting of imaging molecules and pharmacologically active agents gain increasing importance. The ideal delivery system does not...
12.
Schoch J, Staudt M, Samanta A, Wiessler M, Jaschke A
Bioconjug Chem
. 2012 Jun;
23(7):1382-6.
PMID: 22709568
Bioorthogonal reactions are of high interest in biosciences as they allow the introduction of fluorescent dyes, affinity tags, or other unnatural moieties into biomolecules. The site-specific attachment of two or...
13.
Beckmann H, Niederwieser A, Wiessler M, Wittmann V
Chemistry
. 2012 Apr;
18(21):6548-54.
PMID: 22511395
Carbohydrate microarrays are an emerging tool for the high-throughput screening of carbohydrate-protein interactions that represent the basis of many biologically and medicinally relevant processes. The crucial step in the preparation...
14.
Plass T, Milles S, Koehler C, Szymanski J, Mueller R, Wiessler M, et al.
Angew Chem Int Ed Engl
. 2012 Apr;
51(17):4166-70.
PMID: 22473599
No abstract available.
15.
Waldeck W, Heidenreich E, Mueller G, Wiessler M, Toth K, Braun K
J Photochem Photobiol B
. 2012 Feb;
109:28-33.
PMID: 22296652
Red fluorescent proteins can generate reactive oxygen species (ROS) if their fluorochrome is stimulated e.g. by visible light illumination. ROS compounds have very reactive, highly toxic properties leading to cell...
16.
Wiessler M, Hennrich U, Pipkorn R, Waldeck W, Cao L, Peter J, et al.
Theranostics
. 2012 Jan;
1:381-94.
PMID: 22211144
Innovative and personalized therapeutic approaches result from the identification and control of individual aberrantly expressed genes at the transcriptional and post-transcriptional level. Therefore, it is of high interest to establish...
17.
Pipkorn R, Wiessler M, Waldeck W, Hennrich U, Nokihara K, Beining M, et al.
Int J Med Sci
. 2012 Jan;
9(1):1-10.
PMID: 22211082
Progress in genomics and proteomics attended to the door for better understanding the recent rapid expanding complex research field of metabolomics. This trend in biomedical research increasingly focuses to the...
18.
Pipkorn R, Wiessler M, Waldeck W, Lorenz P, Muehlhausen U, Fleischhacker H, et al.
Int J Med Sci
. 2011 Jul;
8(5):387-96.
PMID: 21750642
In the near future personalized medicine with nucleic acids will play a key role in molecular diagnostics and therapy, which require new properties of the nucleic acids, like stability against...
19.
Waldeck W, Mueller G, Wiessler M, Toth K, Braun K
Int J Med Sci
. 2011 Feb;
8(2):97-105.
PMID: 21278894
Fluorescent proteins (FPs) are established tools for new applications, not-restricted to the cell biological research. They could also be ideal in surgery enhancing the precision to differentiate between the target...
20.
Braun K, Wiessler M, Pipkorn R, Ehemann V, Bauerle T, Fleischhacker H, et al.
Int J Med Sci
. 2010 Oct;
7(6):326-39.
PMID: 20922134
Clinical experiences often document, that a successful tumor control requires high doses of drug applications. It is widely believed that unavoidable adverse reactions could be minimized by using gene-therapeutic strategies...