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Marie Stiborova

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Articles 238
Citations 3781
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Recent Articles
1.
Dostalova S, Cerna T, Hynek D, Koudelkova Z, Vaculovic T, Kopel P, et al.
ACS Appl Mater Interfaces . 2022 Jun; 14(27):31510-31511. PMID: 35767884
No abstract available.
2.
Barta F, Dedikova A, Bebova M, Duskova S, Mraz J, Schmeiser H, et al.
Int J Mol Sci . 2021 Oct; 22(19). PMID: 34638820
The plant extract aristolochic acid (AA), containing aristolochic acids I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN), unique renal diseases...
3.
Dracinska H, Indra R, Jelinkova S, cerna V, Arlt V, Stiborova M
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360828
The environmental pollutant benzo[]pyrene (BaP) is a human carcinogen that reacts with DNA after metabolic activation catalysed by cytochromes P450 (CYP) 1A1 and 1B1 together with microsomal epoxide hydrolase. The...
4.
Dedi Kova A, Barta F, Martinek V, Kotalik K, Duskova S, Mraz J, et al.
Chem Res Toxicol . 2020 Sep; 33(11):2804-2818. PMID: 32894017
The plant extract aristolochic acid (AA), containing aristolochic acid I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy and Balkan endemic nephropathy, unique renal diseases associated with...
5.
Indra R, Pompach P, Vavrova K, Jaklova K, Heger Z, Adam V, et al.
Environ Toxicol Pharmacol . 2019 Dec; 74:103310. PMID: 31837525
We studied the in vitro metabolism of the anti-thyroid-cancer drug vandetanib in a rat animal model and demonstrated that N-desmethylvandetanib and vandetanib N-oxide are formed by NADPH- or NADH-mediated reactions...
6.
Beyerle J, Holowatyj A, Haffa M, Frei E, Gigic B, Schrotz-King P, et al.
Cancer Epidemiol Biomarkers Prev . 2019 Nov; 29(2):460-469. PMID: 31740522
Background: Xenobiotic-metabolizing enzymes (XME) play a critical role in the activation and detoxification of several carcinogens. However, the role of XMEs in colorectal carcinogenesis is unclear. Methods: We investigated the...
7.
Sborchia M, De Prez E, Antoine M, Bienfait L, Indra R, Valbuena G, et al.
Arch Toxicol . 2019 Oct; 93(11):3345-3366. PMID: 31602497
Exposure to aristolochic acid (AA) is associated with human nephropathy and urothelial cancer. The tumour suppressor TP53 is a critical gene in carcinogenesis and frequently mutated in AA-induced urothelial tumours....
8.
Indra R, Pompach P, Martinek V, Takacsova P, Vavrova K, Heger Z, et al.
Int J Mol Sci . 2019 Jul; 20(14). PMID: 31295928
The metabolism of vandetanib, a tyrosine kinase inhibitor used for treatment of symptomatic/progressive medullary thyroid cancer, was studied using human hepatic microsomes, recombinant cytochromes P450 (CYPs) and flavin-containing monooxygenases (FMOs)....
9.
Jelakovic B, Dika Z, Arlt V, Stiborova M, Pavlovic N, Nikolic J, et al.
Semin Nephrol . 2019 May; 39(3):284-296. PMID: 31054628
Balkan endemic nephropathy is a chronic tubulointerstitial disease with insidious onset, slowly progressing to end-stage renal disease and frequently associated with urothelial carcinoma of the upper urinary tract (UTUC). It...
10.
Indra R, Cerna T, Heger Z, Hrabeta J, Wilhelm M, Dostalova S, et al.
Toxicology . 2019 Mar; 419:40-54. PMID: 30914192
Although ellipticine (Elli) is an efficient anticancer agent, it exerts several adverse effects. One approach to decrease the adverse effects of drugs is their encapsulation inside a suitable nanocarrier, allowing...