Manfred Rossle
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Explore the profile of Manfred Rossle including associated specialties, affiliations and a list of published articles.
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27
Citations
324
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Recent Articles
11.
Gutsmann T, Razquin-Olazaran I, Kowalski I, Kaconis Y, Howe J, Bartels R, et al.
Antimicrob Agents Chemother
. 2010 Jul;
54(9):3817-24.
PMID: 20606063
Systemic bacterial infections are associated with high mortality. The access of bacteria or constituents thereof to systemic circulation induces the massive release of immunomodulatory mediators, ultimately causing tissue hypoperfusion and...
12.
Balakrishna A, Subramanian Manimekalai M, Hunke C, Gayen S, Rossle M, Jeyakanthan J, et al.
J Bioenerg Biomembr
. 2010 Jun;
42(4):311-20.
PMID: 20571891
The structure of the C-terminus of subunit E (E(101-206)) of Methanocaldococcus jannaschii A-ATP synthase was determined at 4.1 A. E(101-206) consist of a N-terminal globular domain with three alpha-helices and...
13.
Cao X, Coskun U, Rossle M, Buschhorn S, Grzybek M, Dafforn T, et al.
Proc Natl Acad Sci U S A
. 2009 Nov;
106(50):21121-5.
PMID: 19940249
The Golgi-associated four-phosphate adaptor protein 2 (FAPP2) has been shown to possess transfer activity for glucosylceramide both in vitro and in cells. We have previously shown that FAPP2 is involved...
14.
Diepholz M, Venzke D, Prinz S, Batisse C, Florchinger B, Rossle M, et al.
Structure
. 2008 Dec;
16(12):1789-98.
PMID: 19081055
Vacuolar ATPases (V-ATPases) are ATP-dependent proton pumps that maintain the acidity of cellular compartments. They are composed of a membrane-integrated proton-translocating V(0) and an extrinsic cytoplasmic catalytic domain V(1), joined...
15.
Howe J, Richter W, Hawkins L, Rossle M, Alexander C, Fournier K, et al.
Med Chem
. 2008 Nov;
4(6):520-5.
PMID: 18991733
Although hemoglobin (Hb) is mainly present in the cytoplasm of erythrocytes (red blood cells), lower concentrations of pure, cell-free Hb are released permanently into the circulation due to an inherent...
16.
Fukuoka S, Howe J, Andra J, Gutsmann T, Rossle M, Brandenburg K
Biochim Biophys Acta
. 2008 Apr;
1778(10):2051-7.
PMID: 18440300
The neutralization of endotoxin structures such as the active 'endotoxic principle' lipid A by suitable compounds has been shown to be a key step in the treatment of infectious diseases,...
17.
Garidel P, Howe J, Milkereit G, Rossle M, Linser S, Gerber S, et al.
Chem Phys Lipids
. 2007 Oct;
151(1):18-29.
PMID: 17963700
The structural polymorphism of two selected disaccharide glycolipids with a maltose (DMMA) and a melibiose (DMME) carbohydrate headgroup linked to dimyristyl alkyl chains were investigated by FTIR-spectroscopy, differential scanning calorimetry...
18.
Chen X, Howe J, Andra J, Rossle M, Richter W, Galvao da Silva A, et al.
Biochim Biophys Acta
. 2007 Jun;
1768(10):2421-31.
PMID: 17555705
To combat infections by Gram-negative bacteria, it is not only necessary to kill the bacteria but also to neutralize pathogenicity factors such as endotoxin (lipopolysaccharide, LPS). The development of antimicrobial...
19.
Andra J, Howe J, Garidel P, Rossle M, Richter W, Leiva-Leon J, et al.
Biochem J
. 2007 May;
406(2):297-307.
PMID: 17501719
On the basis of formerly investigated peptides corresponding to the endotoxin-binding domain from LALF [Limulus anti-LPS (lipopolysaccharide) factor], a protein from Limulus polyphemus, we have designed and synthesized peptides of...
20.
Schromm A, Howe J, Ulmer A, Wiesmuller K, Seyberth T, Jung G, et al.
J Biol Chem
. 2007 Feb;
282(15):11030-7.
PMID: 17308304
The importance of the biological function and activity of lipoproteins from the outer or cytoplasmic membranes of Gram-positive and Gram-negative bacteria is being increasingly recognized. It is well established that...