Thomas Gutsmann
Overview
Explore the profile of Thomas Gutsmann including associated specialties, affiliations and a list of published articles.
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Articles
120
Citations
2300
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Recent Articles
1.
Andra J, Aisenbrey C, Sudheendra U, Prudhon M, Brezesinski G, Salnikov E, et al.
Biochim Biophys Acta Biomembr
. 2025 Feb;
:184416.
PMID: 39924097
No abstract available.
2.
Allweier J, Bartels M, Torabi H, Tauler M, Metwally N, Roeder T, et al.
Mol Microbiol
. 2024 Dec;
122(6):948-967.
PMID: 39630601
Malaria remains a significant global health problem, mainly due to Plasmodium falciparum, which is responsible for most fatal infections. Infected red blood cells (iRBCs) evade spleen clearance by adhering to...
3.
Gutsmann T
Biophys Rev
. 2024 Dec;
16(5):515-517.
PMID: 39618781
As one of the twelve newly elected councillors, it is my pleasure to provide a brief biographical sketch for the readers of Biophys. Rev. and the members of the Biophysical...
4.
Schaefer S, Vij R, Sprague J, Austermeier S, Dinh H, Judzewitsch P, et al.
Nat Commun
. 2024 Aug;
15(1):6818.
PMID: 39122699
More than two million people worldwide are affected by life-threatening, invasive fungal infections annually. Candida species are the most common cause of nosocomial, invasive fungal infections and are associated with...
5.
Muller R, Konig A, Groth S, Zarnowski R, Visser C, Handrianz T, et al.
Nat Microbiol
. 2024 Feb;
9(3):669-683.
PMID: 38388771
The opportunistic fungal pathogen Candida albicans damages host cells via its peptide toxin, candidalysin. Before secretion, candidalysin is embedded in a precursor protein, Ece1, which consists of a signal peptide,...
6.
Nehls C, Schroder M, Haubenthal T, Haas A, Gutsmann T
Mol Microbiol
. 2024 Feb;
121(3):578-592.
PMID: 38308564
Pathogenic Rhodococcus equi release the virulence-associated protein A (VapA) within macrophage phagosomes. VapA permeabilizes phagosome and lysosome membranes and reduces acidification of both compartments. Using biophysical techniques, we found that...
7.
Andra J, Aisenbrey C, Sudheendra U, Prudhon M, Brezesinski G, Zschech C, et al.
Biochim Biophys Acta Biomembr
. 2023 Dec;
1866(3):184267.
PMID: 38159877
NK-2 is an antimicrobial peptide derived from helices 3 and 4 of the pore-forming protein of natural killer cells, NK-lysin. It has potent activities against Gram-negative and Gram-positive bacteria, fungi...
8.
Hiller M, Diwo M, Wamp S, Gutsmann T, Lang C, Blankenfeldt W, et al.
Mol Microbiol
. 2023 Dec;
121(3):497-512.
PMID: 38130174
Legionella pneumophila, the causative agent of a life-threatening pneumonia, intracellularly replicates in a specialized compartment in lung macrophages, the Legionella-containing vacuole (LCV). Secreted proteins of the pathogen govern important steps...
9.
Donoghue A, Winterhalter M, Gutsmann T
Membranes (Basel)
. 2023 May;
13(5).
PMID: 37233578
The effect of asymmetric membranes containing lipopolysaccharides (LPS) on the outer membrane protein F (OmpF) reconstitution, channel orientation, and antibiotic permeation across the outer membrane was investigated. After forming an...
10.
Moller C, Heinbockel L, Garidel P, Gutsmann T, Mauss K, Weindl G, et al.
Microorganisms
. 2022 Dec;
10(12).
PMID: 36557665
Aspidasept (Pep19-2.5) and its derivative Pep19-4LF ("Aspidasept II") are anti-infective and anti-inflammatory synthetic polypeptides currently in development for application against a variety of moderate to severe bacterial infections that could...