Manching Ku
Overview
Explore the profile of Manching Ku including associated specialties, affiliations and a list of published articles.
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42
Citations
9144
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Recent Articles
1.
Li M, Suzuki K, Wang M, Benner C, Ku M, Ma L, et al.
Sci China Life Sci
. 2025 Mar;
PMID: 40080269
Human pluripotent stem cells (hPSCs) can in theory give rise to any hematopoietic lineages, thereby offering opportunities for disease modeling, drug screening and cell therapies. However, gaps in our knowledge...
2.
Spathopoulou A, Sauerwein G, Marteau V, Podlesnic M, Lindlbauer T, Kipura T, et al.
Mol Psychiatry
. 2024 Apr;
29(10):3128-3140.
PMID: 38684795
Schizophrenia (SCZ) is a neuropsychiatric disorder, caused by a combination of genetic and environmental factors. The etiology behind the disorder remains elusive although it is hypothesized to be associated with...
3.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, et al.
Nat Commun
. 2022 Sep;
13(1):5291.
PMID: 36075901
No abstract available.
4.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, et al.
Nat Commun
. 2022 Jun;
13(1):3646.
PMID: 35752626
The diverse functions of WASP, the deficiency of which causes Wiskott-Aldrich syndrome (WAS), remain poorly defined. We generated three isogenic WAS models using patient induced pluripotent stem cells and genome...
5.
Globig A, Mayer L, Heeg M, Andrieux G, Ku M, Otto-Mora P, et al.
Gastroenterology
. 2022 Jun;
163(4):965-981.e31.
PMID: 35738329
Background & Aims: Exhaustion of CD8 T cells has been suggested to inform different clinical outcomes in Crohn's disease, but detailed analyses are lacking. This study aimed to identify the...
6.
Ravi V, Will P, Kueckelhaus J, Sun N, Joseph K, Salie H, et al.
Cancer Cell
. 2022 Jun;
40(6):639-655.e13.
PMID: 35700707
Glioblastomas are malignant tumors of the central nervous system hallmarked by subclonal diversity and dynamic adaptation amid developmental hierarchies. The source of dynamic reorganization within the spatial context of these...
7.
Corrales E, Levit-Zerdoun E, Metzger P, Kowar S, Ku M, Brummer T, et al.
Cell Commun Signal
. 2021 Dec;
19(1):123.
PMID: 34930313
Background: Vemurafenib (PLX4032) is one of the most frequently used treatments for late-stage melanoma patients with the BRAF mutation; however, acquired resistance to the drug poses as a major challenge....
8.
Sahoo S, Pastor V, Goodings C, Voss R, Kozyra E, Szvetnik A, et al.
Nat Med
. 2021 Nov;
27(12):2248.
PMID: 34799732
No abstract available.
9.
Sahoo S, Pastor V, Goodings C, Voss R, Kozyra E, Szvetnik A, et al.
Nat Med
. 2021 Oct;
27(10):1806-1817.
PMID: 34621053
Germline SAMD9 and SAMD9L mutations (SAMD9/9L) predispose to myelodysplastic syndromes (MDS) with propensity for somatic rescue. In this study, we investigated a clinically annotated pediatric MDS cohort (n = 669)...
10.
Regina C, Hamed E, Andrieux G, Angenendt S, Schneider M, Ku M, et al.
Life Sci Alliance
. 2021 Jun;
4(9).
PMID: 34187933
Rhabdomyosarcomas (RMS) are phenotypically and functionally heterogeneous. Both primary human RMS cultures and low-passage mouse RMS cell lines, which express the fusion oncoprotein Pax3:Foxo1 and lack the tumor suppressor (),...