Manasi Gadkari
Overview
Explore the profile of Manasi Gadkari including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
388
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0
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Recent Articles
1.
Shobnam N, Ratley G, Saksena S, Yadav M, Chaudhary P, Sun A, et al.
J Invest Dermatol
. 2025 Mar;
PMID: 40088241
Topical steroid withdrawal (TSW) is a controversial diagnosis advocated by patients but often confused for atopic dermatitis. We conducted a multimodal pilot study of 16 patients fitting the TSW diagnostic...
2.
Shobnam N, Saksena S, Ratley G, Yadav M, Chaudhary P, Sun A, et al.
medRxiv
. 2024 May;
PMID: 38712043
Background: Topical corticosteroids (TCS) are first-line therapies for numerous skin conditions. Topical Steroid Withdrawal (TSW) is a controversial diagnosis advocated by patients with prolonged TCS exposure who report severe systemic...
3.
Gadkari M, Sun J, Carcamo A, Fraser I, Franco L, Pegoraro G
Methods Mol Biol
. 2024 Mar;
2784:113-132.
PMID: 38502482
Functional genomics and chemical screens can identify and characterize novel cellular factors regulating signaling networks and chemical tools to modulate their function for the treatment of disease. Screening methods have...
4.
Wigerblad G, Cao Q, Brooks S, Naz F, Gadkari M, Jiang K, et al.
J Immunol
. 2022 Jul;
209(4):772-782.
PMID: 35858733
Neutrophils are the most abundant leukocytes in human blood and are essential components of innate immunity. Until recently, neutrophils were considered homogeneous and transcriptionally inactive cells, but both concepts are...
5.
Gadkari M, Sun J, Carcamo A, Alessi H, Hu Z, Fraser I, et al.
RNA
. 2022 Jun;
28(9):1263-1278.
PMID: 35764396
Measurement of gene expression at the single-cell level has advanced the study of transcriptional regulation programs in healthy and disease states. In particular, single-cell approaches have shed light on the...
6.
Cao Q, Boo Irizarry Y, Yazhuk S, Tran T, Gadkari M, Franco L
J Mol Endocrinol
. 2021 Nov;
68(2):B1-B4.
PMID: 34787097
Glucocorticoids are the cornerstone of immunosuppressive and anti-inflammatory therapy in humans, yet the mechanisms of glucocorticoid immunoregulation and toxicity remain unclear. The response to glucocorticoids is highly cell type-dependent, so...
7.
Zaki G, Gudla P, Lee K, Kim J, Ozbun L, Shachar S, et al.
Cytometry A
. 2020 Nov;
97(12):1248-1264.
PMID: 33141508
Deep learning is rapidly becoming the technique of choice for automated segmentation of nuclei in biological image analysis workflows. In order to evaluate the feasibility of training nuclear segmentation models...
8.
Hong S, Sato N, Legrand F, Gadkari M, Makiya M, Stokes K, et al.
Blood
. 2020 Jul;
136(23):2667-2678.
PMID: 32659786
Glucocorticoids are considered first-line therapy in a variety of eosinophilic disorders. They lead to a transient, profound decrease in circulating human eosinophils within hours of administration. The phenomenon of glucocorticoid-induced...
9.
Gupta S, Nakabo S, Blanco L, ONeil L, Wigerblad G, Goel R, et al.
Proc Natl Acad Sci U S A
. 2020 Jul;
117(28):16481-16491.
PMID: 32601182
Differences between female and male immunity may contribute to variations in response to infections and predisposition to autoimmunity. We previously reported that neutrophils from reproductive-age males are more immature and...
10.
Franco L, Gadkari M, Howe K, Sun J, Kardava L, Kumar P, et al.
J Exp Med
. 2019 Jan;
216(2):384-406.
PMID: 30674564
Glucocorticoids remain the most widely used immunosuppressive and anti-inflammatory drugs, yet substantial gaps exist in our understanding of glucocorticoid-mediated immunoregulation. To address this, we generated a pathway-level map of the...