Malay Mandal
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Explore the profile of Malay Mandal including associated specialties, affiliations and a list of published articles.
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46
Citations
1810
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Recent Articles
1.
Tripathi A, Mondal R, Mandal M, Lahiri T, Pal M
Biomolecules
. 2025 Jan;
14(12.
PMID: 39766295
Pathological significance of interaction of Synphilin-1 with mutated alpha-synuclein is well known to have serious consequences in causing the formation of inclusion bodies that are linked to Parkinson's disease (PD)....
2.
Pollard J, Hynes G, Yin D, Mandal M, Gounari F, Alegre M, et al.
JCI Insight
. 2024 May;
9(13).
PMID: 38771643
Alloreactive memory, unlike naive, CD8+ T cells resist transplantation tolerance protocols and are a critical barrier to long-term graft acceptance in the clinic. We here show that semiallogeneic pregnancy successfully...
3.
Wright N, Kennedy D, Ai J, Veselits M, Attaway M, Yoon Y, et al.
bioRxiv
. 2024 May;
PMID: 38712068
Germinal center (GC) B cells segregate into three subsets that compartmentalize the antagonistic molecular programs of selection, proliferation, and somatic hypermutation. In bone marrow, the epigenetic reader BRWD1 orchestrates and...
4.
Mandal M, Maienschein-Cline M, Hu Y, Mohsin A, Veselits M, Wright N, et al.
Nat Immunol
. 2023 Nov;
25(1):129-141.
PMID: 37985858
Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination. Transitions between each state require large, coordinated changes in epigenetic landscapes and...
5.
Wright N, Mandal M, Clark M
Trends Immunol
. 2023 Aug;
44(9):668-677.
PMID: 37573227
In mammals, B cells strictly segregate proliferation from somatic mutation as they develop within the bone marrow and then mature through germinal centers (GCs) in the periphery. Failure to do...
6.
Fike A, Chodisetti S, Wright N, Bricker K, Domeier P, Maienschein-Cline M, et al.
Cell Rep
. 2023 May;
42(5):112512.
PMID: 37200190
Germinal centers (GCs), sites of antibody affinity maturation, are organized into dark (DZ) and light (LZ) zones. Here, we show a B cell-intrinsic role for signal transducer and activator of...
7.
Pollard J, Hynes G, Yin D, Mandal M, Gounari F, Alegre M, et al.
Res Sq
. 2023 Apr;
PMID: 37066154
Alloreactive memory T cells, unlike naive T cells, fail to be restrained by transplantation tolerance protocols or regulatory T cells, and therefore represent a critical barrier to long-term graft acceptance....
8.
Okoreeh M, Kennedy D, Olumide Emmanuel A, Veselits M, Moshin A, Ladd R, et al.
Sci Immunol
. 2022 Aug;
7(74):eabm1664.
PMID: 35930652
During B lymphopoiesis, B cell progenitors progress through alternating and mutually exclusive stages of clonal expansion and immunoglobulin (Ig) gene rearrangements. Great diversity is generated through the stochastic recombination of...
9.
Zheng Z, Zhang L, Cui X, Yu X, Hsu P, Lyu R, et al.
Cell Rep
. 2020 Jul;
31(13):107819.
PMID: 32610122
The RNA N-methyladenosine (mA) methylation is installed by the METTL3-METTL14 methyltransferase complex. This modification has critical regulatory roles in various biological processes. Here, we report that deletion of Mettl14 dramatically...
10.
McLean K, Mandal M
Trends Immunol
. 2020 May;
41(7):629-642.
PMID: 32451219
As the unique source of diverse immunoglobulin repertoires, B lymphocytes are an indispensable part of humoral immunity. B cell progenitors progress through sequential and mutually exclusive states of proliferation and...