Marcus R Clark
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Explore the profile of Marcus R Clark including associated specialties, affiliations and a list of published articles.
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76
Citations
2331
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Recent Articles
1.
Torcasso M, Ai J, Casella G, Cao T, Chang A, Halper-Stromberg A, et al.
J Med Imaging (Bellingham)
. 2024 Dec;
11(6):067502.
PMID: 39664650
Purpose: The rapid development of highly multiplexed microscopy has enabled the study of cells embedded within their native tissue. The rich spatial data provided by these techniques have yielded exciting...
2.
Wright N, Kennedy D, Ai J, Veselits M, Attaway M, Yoon Y, et al.
bioRxiv
. 2024 May;
PMID: 38712068
Germinal center (GC) B cells segregate into three subsets that compartmentalize the antagonistic molecular programs of selection, proliferation, and somatic hypermutation. In bone marrow, the epigenetic reader BRWD1 orchestrates and...
3.
Durkee M, Ai J, Casella G, Cao T, Chang A, Halper-Stromberg A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260318
The rapid development of highly multiplexed microscopy systems has enabled the study of cells embedded within their native tissue, which is providing exciting insights into the spatial features of human...
4.
Hu Y, Figueroa D, Zhang Z, Veselits M, Bhattacharyya S, Kashiwagi M, et al.
Cell
. 2023 Nov;
186(24):5269-5289.e22.
PMID: 37995656
A generic level of chromatin organization generated by the interplay between cohesin and CTCF suffices to limit promiscuous interactions between regulatory elements, but a lineage-specific chromatin assembly that supersedes these...
5.
Mandal M, Maienschein-Cline M, Hu Y, Mohsin A, Veselits M, Wright N, et al.
Nat Immunol
. 2023 Nov;
25(1):129-141.
PMID: 37985858
Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination. Transitions between each state require large, coordinated changes in epigenetic landscapes and...
6.
Zhang D, Kinloch A, Srinath A, Shenkar R, Girard R, Lightle R, et al.
J Autoimmun
. 2023 Sep;
140:103116.
PMID: 37748978
No abstract available.
7.
Wright N, Mandal M, Clark M
Trends Immunol
. 2023 Aug;
44(9):668-677.
PMID: 37573227
In mammals, B cells strictly segregate proliferation from somatic mutation as they develop within the bone marrow and then mature through germinal centers (GCs) in the periphery. Failure to do...
8.
Yoon Y, Velez T, Upadhyay V, Vazquez S, Lee C, Selvan K, et al.
medRxiv
. 2023 May;
PMID: 37214861
Interstitial lung diseases (ILD) are heterogeneous conditions that may lead to progressive fibrosis and death of affected individuals. Despite diversity in clinical manifestations, enlargement of lung-associated lymph nodes (LLN) in...
9.
Fike A, Chodisetti S, Wright N, Bricker K, Domeier P, Maienschein-Cline M, et al.
Cell Rep
. 2023 May;
42(5):112512.
PMID: 37200190
Germinal centers (GCs), sites of antibody affinity maturation, are organized into dark (DZ) and light (LZ) zones. Here, we show a B cell-intrinsic role for signal transducer and activator of...
10.
Lee V, Rodriguez D, Ganci N, Zeng S, Ai J, Chao J, et al.
Nat Immunol
. 2023 Feb;
24(3):487-500.
PMID: 36759711
The T cell repertoire of healthy mice and humans harbors self-reactive CD4 conventional T (T) cells capable of inducing autoimmunity. Using T cell receptor profiling paired with in vivo clonal...