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Makram Obeid

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Articles 37
Citations 196
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Recent Articles
1.
El Jammal R, Tfaily A, Cochran A, Nguyen T, Miller D, El Ayoubi N, et al.
Epilepsy Behav . 2024 Oct; 161:110086. PMID: 39476704
To optimize the clinical approach to non-convulsive status epilepticus (NCSE), it is essential to gain insight into its long-term effects on cognition and behaviors. Here, we investigated limbic NCSE-induced hippocampal...
2.
Rawlins L, Maroofian R, Cannon S, Daana M, Zamani M, Ghani S, et al.
Genet Med . 2024 Sep; 27(2):101278. PMID: 39315527
Purpose: Biallelic INPP4A variants have recently been associated with severe neurodevelopmental disease in single-case reports. Here, we expand and elucidate the clinical-genetic spectrum and provide a pathomechanistic explanation for genotype-phenotype...
3.
Charouf D, Miller D, Haddad L, White F, Boustany R, Obeid M
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273593
Advances in genetics led to the identification of hundreds of epilepsy-related genes, some of which are treatable with etiology-specific interventions. However, the diagnostic yield of next-generation sequencing (NGS) in unexplained...
4.
Khoury F, Saleh S, Badawe H, Obeid M, Khraiche M
ACS Appl Mater Interfaces . 2024 Aug; PMID: 39146224
Organic electrochemical transistors (OECTs) have emerged as powerful tools for biosignal amplification, including electrocorticography (ECoG). However, their widespread application has been limited by the complexities associated with existing fabrication techniques,...
5.
Itani S, Hamie M, El Jammal R, Abdine W, Doumit M, Charafeddine A, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927503
is the etiologic agent of toxoplasmosis, a highly prevalent parasitosis. () transits in the brain from acute (AT) to chronic toxoplasmosis (CT), under host immune control. In immunocompromised patients, reactivation...
6.
Mrad Y, El Jammal R, Hajjar H, Alturk S, Salah H, Chehade H, et al.
Epilepsy Res . 2023 Jul; 195:107198. PMID: 37467703
Background: The timely abortion of status epilepticus (SE) is essential to avoid brain damage and long-term neurodevelopmental sequalae. However, available anti-seizure treatments fail to abort SE in 30% of children....
7.
Jaafar F, Obeid M, Beydoun A
Pediatr Neurol . 2023 Jun; 145:30-35. PMID: 37269621
Background: Rasmussen encephalitis (RE) is a rare progressive presumed autoimmune disorder characterized by pharmacoresistant epilepsy and progressive motor and cognitive deterioration. Despite immunomodulation, more than half of the patients with...
8.
Jaafar F, Abboud M, Obeid M
Pediatr Neurol . 2022 Oct; 137:17-21. PMID: 36182697
Background: Seizures occur in up to 13% of children with non-central nervous system (CNS) malignancies, but little is known about their causes and optimal diagnostic and therapeutic approaches. Here we...
9.
Jaafar F, Obeid M
Pediatr Neurol . 2022 Aug; 135:22-24. PMID: 35970100
No abstract available.
10.
Asdikian R, Hajjar H, Alturk S, Asdikian J, Jaafar F, Salah H, et al.
Epilepsy Behav . 2021 Nov; 125:108415. PMID: 34788732
The effects of non-convulsive status epilepticus (NCSE) on the developing brain remain largely elusive. Here we investigated potential hippocampal injury and learning deficits following one or two episodes of NCSE...