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Nabil Karnib

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Articles 12
Citations 367
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Recent Articles
1.
Jalloul D, Hajjar H, Asdikian R, Maawie M, Nasrallah L, Medlej Y, et al.
Int J Mol Sci . 2021 Jul; 22(12). PMID: 34208666
Post-traumatic epilepsy (PTE) and neurocognitive deficits are devastating sequelae of head injuries that are common in adolescents. Investigating desperately needed treatments is hindered by the difficulties in inducing PTE in...
2.
Karnib N, van Staaden M
Brain Behav Evol . 2021 Feb; 95(5):222-229. PMID: 33567426
Addiction is a debilitating condition that extracts enormous social and economic tolls. Despite several decades of research, our knowledge of its etiology, preventive measures, and treatments is limited. A relatively...
3.
Bilen M, Ibrahim P, Barmo N, Haidar E, Karnib N, El Hayek L, et al.
Psychopharmacology (Berl) . 2020 Jun; 237(10):3007-3020. PMID: 32564114
Rationale: Previous studies suggested that methionine (Met) levels are decreased in depressed patients. However, whether the decrease in this amino acid is important for phenotypic behaviors associated with depression has...
4.
Salah H, Medlej Y, Karnib N, Darwish N, Asdikian R, Wehbe S, et al.
Methods Mol Biol . 2019 Jul; 2011:413-427. PMID: 31273713
Pediatric epilepsy is associated with prominent comorbid psychiatric and cognitive disturbances. Neurobehavioral testing is employed to characterize the cognitive and emotional behavioral derangements that accompany seizures in age-tailored and clinically...
5.
Medlej Y, Salah H, Wadi L, Saad S, Asdikian R, Karnib N, et al.
Methods Mol Biol . 2019 Jul; 2011:345-367. PMID: 31273709
Psychiatric and cognitive disturbances are the most common comorbidities of epileptic disorders in children. The successful treatment of these comorbidities faces many challenges including their etiologically heterogonous nature. Translational neurobehavioral...
6.
Nasrallah P, Haidar E, Stephan J, El Hayek L, Karnib N, Khalifeh M, et al.
Neurobiol Stress . 2019 Jun; 11:100170. PMID: 31193350
How individuals respond to chronic stress varies. Susceptible individuals ultimately develop depression; whereas resilient individuals live normally. In this study, our objective was to examine the effect of branched-chain amino...
7.
Medlej Y, Asdikian R, Wadi L, Salah H, Dosh L, Hashash R, et al.
BMC Neurosci . 2019 Mar; 20(1):8. PMID: 30832562
Background: The electroencephalogram (EEG) is a widely used laboratory technique in rodent models of epilepsy, traumatic brain injury (TBI), and other neurological diseases accompanied by seizures. Obtaining prolonged continuous EEG...
8.
Medlej Y, Salah H, Wadi L, Saad S, Bashir B, Allam J, et al.
Epilepsy Behav . 2019 Feb; 92:332-340. PMID: 30769278
Hypoxic encephalopathy of the newborn is a major cause of long-term neurological sequelae. We have previously shown that CEP-701 (lestaurtinib), a drug with an established safety profile in children, attenuates...
9.
El Hayek L, Khalifeh M, Zibara V, Abi Assaad R, Emmanuel N, Karnib N, et al.
J Neurosci . 2019 Jan; 39(13):2369-2382. PMID: 30692222
Exercise promotes learning and memory formation. These effects depend on increases in hippocampal BDNF, a growth factor associated with cognitive improvement and the alleviation of depression symptoms. Identifying molecules that...
10.
Karnib N, El-Ghandour R, El Hayek L, Nasrallah P, Khalifeh M, Barmo N, et al.
Neuropsychopharmacology . 2019 Jan; 44(6):1152-1162. PMID: 30647450
Chronic stress promotes depression in some individuals, but has no effect in others. Susceptible individuals exhibit social avoidance and anxious behavior and ultimately develop depression, whereas resilient individuals live normally....